MEG analysis of neural dynamics in attention-deficit/hyperactivity disorder with fuzzy entropy

Medical Engineering & Physics
Jesús MongeRoberto Hornero

Abstract

The aim of this study was to analyze the neural dynamics in attention-deficit/hyperactivity disorder (ADHD). For this purpose, magnetoencephalographic (MEG) background activity was analyzed using fuzzy entropy (FuzzyEn), an entropy measure that quantifies signal irregularity, in 13 ADHD patients and 14 control children. Additionally, relative power (RP) was computed in conventional frequency bands (delta, theta, alpha, beta and gamma). FuzzyEn results showed that MEG activity was more regular in ADHD patients than in controls. Moreover, we found an increase of power in delta band and a decrease in the remaining frequency bands. Statistically significant differences (p-values <0.05; nonparametric permutation test for multiple comparisons) were detected for FuzzyEn in the posterior and left temporal regions, and for RP in the posterior, anterior and left temporal regions. Our results support the hypothesis that ADHD involves widespread functional brain abnormalities, affecting more areas than fronto-striatal circuits, such as the left temporal and posterior regions.

References

Nov 15, 1990·The New England Journal of Medicine·A J ZametkinR M Cohen
Jan 1, 1989·Archives of Neurology·H C LouJ B Nielsen
Sep 11, 1998·Journal of Child Neurology·S H MostofskyM B Denckla
Nov 6, 1998·Journal of Child Psychology and Psychiatry, and Allied Disciplines·R Granero PérezN de la Osa Chaparro
Nov 20, 1998·Biological Psychiatry·S V Faraone, J Biederman
Nov 24, 1999·Biological Psychiatry·J Biederman, T Spencer
Apr 6, 2001·Clinical Neuropharmacology·A A Baumeister, M F Hawkins
Dec 18, 2001·Human Brain Mapping·Thomas E Nichols, Andrew P Holmes
Jan 5, 2002·Neurobiology of Aging·Ary L GoldbergerLewis A Lipsitz
Oct 9, 2002·JAMA : the Journal of the American Medical Association·F Xavier CastellanosJudith L Rapoport
Jan 9, 2003·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Regina BussingChristiana Leonard
Feb 1, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Robert J BarryStuart J Johnstone
Feb 1, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Robert J BarryAdam R Clarke
May 20, 2003·Child: Care, Health and Development·J R ParrS Inman
Nov 20, 2003·Neuroscience and Biobehavioral Reviews·Klaus Henning KrauseManfred Ackenheil
Nov 10, 2004·Brain & Development·Sachiko Onoe, Toshinori Nishigaki
Jun 14, 2005·Biological Psychiatry·Joseph Biederman
Jun 14, 2005·Biological Psychiatry·Larry J SeidmanNikos Makris
Aug 24, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C J Stam
Feb 17, 2006·Clinical Psychology Review·Amy L Krain, F Xavier Castellanos
Apr 3, 2007·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Neil Gordon
Jul 3, 2007·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Weiting ChenWangxin Yu
Sep 18, 2007·Progress in Neurobiology·Paolo M RossiniJohn Polich
Jun 10, 2008·Medical Engineering & Physics·Weiting ChenZhizhong Wang
Dec 17, 2010·Frontiers in Human Neuroscience·Leighton B N HinkleySrikantan S Nagarajan

❮ Previous
Next ❯

Citations

Apr 28, 2016·Computational Intelligence and Neuroscience·Amine KhadmaouiRoberto Hornero
Aug 24, 2021·Clinical EEG and Neuroscience·R Catherine JoyM S P Subathra

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Related Papers

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Carlos GómezRoberto Hornero
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Carlos GómezRoberto Hornero
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Jesús PozaJavier Escudero
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Carlos GómezRoberto Hornero
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Ali H Al-TimemyJavier Escudero
© 2022 Meta ULC. All rights reserved