MEGA6: Molecular Evolutionary Genetics Analysis version 6.0

Molecular Biology and Evolution
Koichiro TamuraSudhir Kumar

Abstract

We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis. In version 6.0, MEGA now enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny. A new Timetree Wizard in MEGA6 facilitates this timetree inference by providing a graphical user interface (GUI) to specify the phylogeny and calibration constraints step-by-step. This version also contains enhanced algorithms to search for the optimal trees under evolutionary criteria and implements a more advanced memory management that can double the size of sequence data sets to which MEGA can be applied. Both GUI and command-line versions of MEGA6 can be downloaded from www.megasoftware.net free of charge.

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Dec 26, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Huie Li, Qiqiang Guo
Dec 26, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Shibing ZhuMinghai Zhang
Dec 26, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Ying-Nan SongJiong-Tang Li
Jan 3, 2016·Molecular Phylogenetics and Evolution·M J T N TimmermansO Brattström
Dec 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Lei WangYuming Zhao
Dec 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Sudheesh K PrabhudasPurushothaman Natarajan
Dec 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Tao ChenXiao-Rong Wang
Dec 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Xian GuoDengxue Lu
Dec 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Qi Mao, Guiqi Bi
Dec 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Bijay Kumar BeheraJ K Jena
Dec 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Bei XinBingyan Xie
Oct 16, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Marianna Soroka, Artur Burzyński
Jan 16, 2016·Molecular Phylogenetics and Evolution·Alexander T SalisNicolas J Rawlence
Oct 17, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Wei-Tao LiMei-Hua Xiong
Oct 17, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Min LiZuozhi Chen
Jan 6, 2016·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Guo-Qing BaiSi-Feng Li
Oct 21, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Zuhao Huang, Dianhua Ke
Oct 21, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Ke ShaoWei-Tao Li
Oct 21, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Girish KumarSwaraj Priyaranjan Kunal
Nov 19, 2015·Mobile DNA·Lavanya RishishwarI King Jordan
Sep 11, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Wei-Tao LiYan-Fu Que
Sep 11, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Beata SmietankaArtur Burzyński
Sep 30, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Yu XuFeiyun Tu
Sep 16, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Muhammad Fiaz KhanYifeng Chen
Sep 16, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Chih-Yao HsuShu-Miaw Chaw
Sep 16, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Muhammad Fiaz KhanYifeng Chen
Sep 16, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Raxsina PolseelaJohn-James Wilson
Sep 16, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Ersin Doğaç
Jun 30, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Kang-Ning ShenChung-Der Hsiao
Jul 1, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Jumin JunJi-Don Kum
Jul 1, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·H Abdul Jaffar Ali, N Shabeer Ahmed
Dec 8, 2015·Micron : the International Research and Review Journal for Microscopy·Robinson C JoseNarayan C Talukdar
Mar 5, 2016·Plant Physiology and Biochemistry : PPB·Liang LiShuting Qi
Aug 12, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Yan-Fu QueWei-Tao Li
Feb 19, 2016·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Betania Paiva DrumondLuiz Felipe Leomil Coelho
Mar 26, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Hua TianXiaolin Liao
Jul 11, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Claudio Quezada-RomegialliIrma Vila
Aug 15, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Haipeng ZhaoWen Luo
Jun 19, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Zuhao HuangDianhua Ke
Jun 26, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Dong-Mei XuYan-Fu Que
Jun 26, 2014·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Linping WangChengqiang Feng
Jan 24, 2016·FEBS Letters·Shuhei YasumotoToshiya Muranaka
Jan 27, 2016·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Rahma ThabetVincent Leignel
Oct 28, 2015·Research in Microbiology·María Camila MoralesMargarita Carú
Dec 23, 2014·Computational and Mathematical Methods in Medicine·Lei WangJinhua Zheng
Feb 13, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Rezak DraliDidier Raoult
Feb 18, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Viviana ValastroIsabella Monne
Jan 17, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Elena ZhirakovskaiaNina Tikunova
Nov 29, 2015·Nucleic Acids Research·Dennis KlementzStefan Günther
Dec 15, 2015·Acta Tropica·Manaw SangfuangNarin Preyavichyapugdee
Dec 5, 2015·Molecular Biology and Evolution·Andres VeidenbergAri Löytynoja
Jan 14, 2016·Genome Biology and Evolution·Jessica M WarrenDaniel B Sloan
Jan 31, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Xiaotong ZhuLiwang Cui
Mar 26, 2016·Comparative Immunology, Microbiology and Infectious Diseases·Ivana LojkićTomislav Bedeković
Sep 27, 2015·Chemosphere·Fisseha Andualem Bezza, Evans M Nkhalambayausi Chirwa
Mar 5, 2016·Plant Science : an International Journal of Experimental Plant Biology·Deepak BajajSwarup K Parida
Mar 5, 2016·Plant Science : an International Journal of Experimental Plant Biology·Chen DongLiqiang Jia
Jan 28, 2016·Acta Tropica·Angélica Pech-MayJanine M Ramsey
Feb 18, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Gábor ReuterPéter Pankovics
Jan 19, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Stephanie GoyaMariana Viegas
Jan 8, 2016·Molecular Biology and Evolution·Amanda D MelinNathaniel J Dominy
Jan 23, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Kiril M DimitrovClaudio L Afonso
Feb 2, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Gianguglielmo ZehenderElisabetta Tanzi
Jun 6, 2014·International Journal of Molecular Sciences·Xianguang NieYucheng Wang
Mar 19, 2015·Viruses·Christelle Le DantecYves Renaudineau
Dec 26, 2015·International Journal of Environmental Research and Public Health·Pablo LópezYasuhiro Yamamura
Oct 6, 2015·International Journal of Environmental Research and Public Health·Bukola Rhoda Aremu, Olubukola Oluranti Babalola
Aug 30, 2016·Indian Journal of Microbiology·Gunjan Kumar SauravRaman Rajagopal
Jan 22, 2015·Viruses·Seyed Mohammad Jazaeri FarsaniLia van der Hoek
Jun 5, 2015·Marine Drugs·Lijian XuQinggui Wang
Sep 22, 2015·International Journal of Molecular Sciences·Dong GuoShi-Qing Peng
Feb 6, 2016·International Journal of Molecular Sciences·Aiping SongFadi Chen
Feb 19, 2015·Viruses·Melisa Berenice BonicaElisabeth Heylen
Apr 9, 2015·International Journal of Molecular Sciences·Xu YangLinbao Xue
Jun 14, 2014·International Journal of Molecular Sciences·Dongjuan YuanYonghua Wang
Jul 23, 2015·International Journal of Molecular Sciences·Camila Agnes Lumi AbeIone Parra Barbosa-Tessmann
Jan 6, 2016·International Journal of Molecular Sciences·Jia LiQiong Shi
Sep 13, 2014·International Journal of Molecular Sciences·Adriana CalderaroFlora De Conto
Apr 30, 2015·Biomolecules·Bryan R Lenneman, Lucia B Rothman-Denes
May 13, 2014·Sensors·Nina Yusrina Muhamad YunosKok-Gan Chan
Apr 29, 2015·Viruses·Yoshinori NakazawaDarin S Carroll
Jan 19, 2016·Journal of Hepatology·Håvard MidgardOlav Dalgard
Feb 9, 2016·Insect Biochemistry and Molecular Biology·Matan ShelomiYannick Pauchet
Jun 11, 2015·Biomolecules·Manohar Chakrabarti, Arthur G Hunt
Feb 19, 2015·International Journal of Molecular Sciences·Jia-Hong ZhuZhi-Li Zhang
Oct 28, 2015·International Journal of Molecular Sciences·Ying ZhaoPatrick C Y Woo
Apr 4, 2015·International Journal of Molecular Sciences·Giovanna Câmara GiudicelliLoreta Brandão de Freitas
Mar 8, 2016·Medical Mycology Case Reports·Sergio Álvarez-PérezJosé L Blanco
May 3, 2014·International Journal of Molecular Sciences·Xiang TanPing Zhao
May 6, 2014·Mitochondrion·Ozgur GuneyHikmet Hakan Aydin
May 20, 2015·Life·Alexander J Probst, Christine Moissl-Eichinger
Sep 26, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Lívia Soman de MedeirosEdson Rodrigues-Filho
Jun 26, 2015·Toxins·Quentin Kaas, David J Craik
Nov 15, 2014·International Journal of Environmental Research and Public Health·Hugo C OsórioMaria J Alves
Feb 14, 2016·Bioscience, Biotechnology, and Biochemistry·Shiho MukaidaMasanori Arita
Oct 29, 2014·International Journal of Molecular Sciences·Ayed M Al-AbdallatShireen Hasan
Oct 29, 2015·International Journal of Systematic and Evolutionary Microbiology·Ram Hari Dahal, Jaisoo Kim
Oct 30, 2015·International Journal of Systematic and Evolutionary Microbiology·Somboon TanasupawatTakuji Kudo
Oct 31, 2015·International Journal of Systematic and Evolutionary Microbiology·Heeyoung KangKiseong Joh
Oct 31, 2015·International Journal of Systematic and Evolutionary Microbiology·Lei ZhangXiao-Xia Zhang
Oct 31, 2015·International Journal of Systematic and Evolutionary Microbiology·Sonia GiubergiaLone Gram
Feb 13, 2016·Medical Mycology·Bahram AhmadiNiloofar Jalalizand
Nov 1, 2015·International Journal of Systematic and Evolutionary Microbiology·Heeyoung KangKiseong Joh
Nov 1, 2015·International Journal of Systematic and Evolutionary Microbiology·Edel Pérez-LópezTim J Dumonceaux
Nov 5, 2015·International Journal of Systematic and Evolutionary Microbiology·Yochan JoungKiseong Joh
Nov 5, 2015·International Journal of Systematic and Evolutionary Microbiology·Hina SinghTae-Hoo Yi
Nov 5, 2015·International Journal of Systematic and Evolutionary Microbiology·Bo LiuQian-Qian Chen
Nov 6, 2015·International Journal of Systematic and Evolutionary Microbiology·Lucie KešnerováPhilipp Engel
Feb 13, 2016·Scientific Reports·Lihong ChenWeixiong Zhang
Nov 7, 2015·International Journal of Systematic and Evolutionary Microbiology·Fuhong XieGuocan Chen
Nov 8, 2015·Archives of Microbiology·Ortiz-Alcántara Joanna MaríaRamírez-González José Ernesto
Nov 8, 2015·International Journal of Systematic and Evolutionary Microbiology·Enrico TortoliDaniela M Cirillo
Nov 11, 2015·International Journal of Systematic and Evolutionary Microbiology·Wongsakorn PhongsopitanunSomboon Tanasupawat
Nov 18, 2015·Parasitology Research·Anne Ø ChristiansenBirgitte J Vennervald
Sep 1, 2015·Journal of Industrial Microbiology & Biotechnology·Jeffrey D RudolfBen Shen
Oct 18, 2015·International Journal of Systematic and Evolutionary Microbiology·Lyudmila KozyrevaBair Namsaraev
Oct 18, 2015·International Journal of Systematic and Evolutionary Microbiology·B DivyasreeCh V Ramana
Oct 20, 2015·International Journal of Systematic and Evolutionary Microbiology·Hina SinghTae-Hoo Yi
Oct 22, 2015·International Journal of Systematic and Evolutionary Microbiology·Yong-Guang ZhangWen-Jun Li
Jun 9, 2016·Journal of Plankton Research·Shunyan CheungHongbin Liu
Oct 24, 2015·International Journal of Systematic and Evolutionary Microbiology·Maki TeramotoMiyuki Nishijima
Oct 24, 2015·International Journal of Systematic and Evolutionary Microbiology·Zhi HuangFei Zhao
Oct 27, 2015·International Journal of Systematic and Evolutionary Microbiology·Min-Kyeong KimSeung Bum Kim
Oct 27, 2015·Journal of Enzyme Inhibition and Medicinal Chemistry·Ayşenur EminoğluAli Osman Beldüz
Dec 1, 2015·Critical Reviews in Biochemistry and Molecular Biology·Laurie S Kaguni, Marcos T Oliveira
Feb 28, 2016·Enzyme and Microbial Technology·Mohammad Asadur RahmanZiduo Liu
Jan 27, 2015·FEBS Letters·Lenea Nørskov-LauritsenHans Bräuner-Osborne
May 18, 2016·Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology·Akhilesh Kumar ChaurasiaPrafullachandra Vishnu Sane
Mar 20, 2016·Plant Science : an International Journal of Experimental Plant Biology·Yuji Yamasaki, Stephen K Randall
Feb 6, 2016·Virology·Guendalina ZaccariaAlessio Lorusso
Oct 27, 2015·FEMS Microbiology Ecology·Valeria AgamennoneWilfred F M Röling
Feb 24, 2016·Frontiers in Microbiology·Ashish V PolkadeKamlesh Jangid
Jan 9, 2016·Science·Frank MaixnerAlbert Zink
Feb 11, 2016·The New England Journal of Medicine·Jernej MlakarTatjana Avšič Županc
Jan 27, 2016·Environmental Technology·Eric Pomaranski, Sonia M Tiquia-Arashiro
Feb 10, 2016·Scientific Reports·Ya-Nan HouYun-Xia Luan
Feb 14, 2016·Ticks and Tick-borne Diseases·Eva HajduskovaLenka Zdrazilova-Dubska
Nov 19, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Lotte RomainRuimy Raymond
Sep 13, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Junping PengQi Jin
Feb 14, 2016·Veterinary Parasitology·Heidi Larsen EnemarkMohammad Nafi Solaiman Al-Sabi
Feb 10, 2016·Mycoses·Marta SanchisJosep Guarro
Apr 14, 2015·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Ke LiQi Jin
Feb 22, 2016·Plant Physiology and Biochemistry : PPB·Aiping SongFadi Chen
Nov 8, 2015·Virus Research·Shin-Yi Lee Marzano, Leslie L Domier
Feb 13, 2016·Journal of Bioscience and Bioengineering·Makoto IwataTakao Fujii
Feb 13, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Ahmed A Al-QahtaniSomchai Jongwutiwes
Aug 13, 2014·International Journal of Food Microbiology·Nuwan R VithanageNivedita Datta
Mar 2, 2016·Plant Physiology and Biochemistry : PPB·Francisco Ignacio Jasso-RoblesMargarita Rodríguez-Kessler
Feb 24, 2016·Japanese Journal of Infectious Diseases·Mostafa Salehi-VaziriMehdi Fazlalipour