Melanin-concentrating hormone (MCH) immunoreactive hypophysial neurosecretory system in the teleost Poecilia latipinna: light and electron microscopic study

General and Comparative Endocrinology
T F Batten, B Baker

Abstract

Neurons containing immunoreactivity for melanin-concentrating hormone (MCH) were located in the brain of the teleost Poecilia latipinna by light microscopic (peroxidase antiperoxidase) and electron microscopic (immunogold) methods. Neuronal cell bodies were found in the tuberal hypothalamus, mostly within the nucleus lateralis tuberis, pars lateralis, containing MCH-immunoreactive granules up to 150 nm in diameter. From here bundles of immunoreactive fibers could be traced through the preoptic area as far forward as the olfactory bulb, and through the posterior hypothalamus up into the pretectal thalamus and midbrain. The main projection was, however, to the neurohypophysis, where MCH fibers were observed to form contacts with pituicytes, basement membranes around blood vessels, and the endocrine cells of the pars intermedia. Occasionally MCH-immunoreactive terminals were also seen near the corticotrophs of the rostral pars distalis. These results support the hypothesis that MCH may act as a systemic hormone, a central neurotransmitter, and a modulator of pituitary function.

References

Jan 1, 1979·General and Comparative Endocrinology·T Rance, B I Baker
Feb 1, 1975·General and Comparative Endocrinology·B I Baker, J N Ball
Mar 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·N ZamirD M Jacobowitz
Jan 1, 1987·General and Comparative Endocrinology·L D BarberA N Eberle
Jan 1, 1985·Histochemistry·P M LackieJ M Polak
Jun 1, 1983·General and Comparative Endocrinology·B I Baker, T A Rance
Jul 1, 1984·General and Comparative Endocrinology·B I BakerT J Bowley

❮ Previous
Next ❯

Citations

Feb 10, 1998·The Journal of Comparative Neurology·M VallarinoH Vaudry
Jun 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·C D MinthJ E Dixon
Apr 1, 1995·Journal of Neuroendocrinology·M SuzukiA Levy
May 31, 1993·Annals of the New York Academy of Sciences·H KawauchiM Ono
May 31, 1993·Annals of the New York Academy of Sciences·B I Baker
Jul 15, 1999·The Journal of Comparative Neurology·J CardotD Fellmann
Jun 24, 2005·The Journal of Comparative Neurology·Gema HuesaThomas E Finger
Jul 23, 2004·Environmental Toxicology·V UleviciusJ Andriejauskiene
Jun 15, 2017·Frontiers in Systems Neuroscience·Giovanne B Diniz, Jackson C Bittencourt
Dec 19, 2019·Frontiers in Neuroscience·Giovanne B Diniz, Jackson C Bittencourt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.