Melanocytic nevi and risk of cutaneous malignant melanoma in southern Spain

American Journal of Epidemiology
J M RódenasS Serrano

Abstract

The main objective of this study was to assess whether cutaneous malignant melanoma (CMM) shows a stronger relation with the melanocytic nevi count at the site where CMM was diagnosed than with the melanocytic nevi count at other sites, stratifying by histologic CMM type, in a southern Mediterranean population. Cases and controls were selected from a population in southern Spain in 1988-1993. The study population included 116 incident cases with non-familial CMM (International Classification of Diseases 9th Revision (ICD-9) code 172), and 116 controls matched 1:1 for sex and age (+/- 4 years). Data were collected by personal interview, and melanocytic nevi were counted over the entire body surface by clinical skin examination performed by a dermatologist. Crude and multiple risk factor-adjusted odds ratios and 95% confidence intervals were computed by conditional logistic regression analysis. After adjustment by skin type, unexposed skin color, and sun exposure, CMM was found to occur significantly more frequently in individuals with a high number of melanocytic nevi at the same site where CMM originated (odds ratio (OR) for >8 nevi = 12.0, 95% confidence interval (CI) 1.3-108.2). The ability to predict the number of melanocyti...Continue Reading

Citations

Sep 23, 2009·Archives of Dermatology·Jenny AalborgLori A Crane
Sep 1, 2005·Cancer Causes & Control : CCC·Luigi NaldiUNKNOWN Oncology Study Group of the Italian Group for Epidemiologic Research in Dermatology
May 8, 1999·The British Journal of Dermatology·C Fariñas-AlvarezM Delgado-Rodríguez
Feb 12, 2009·Melanoma Research·Zhen Zhen ZhaoGrant W Montgomery
Oct 1, 2013·Dermatologic Clinics·Susana Puig, Josep Malvehy
May 26, 2012·Actas dermo-sifiliográficas·I BallesterE Nagore
Jun 24, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Saverio CainiBruce K Armstrong
Apr 29, 2006·The Journal of Investigative Dermatology·Giorgia RandiUNKNOWN Oncology Study Group of the Italian Group for Epidemiologic Research in Dermatology (GISED)
Jul 31, 2007·Dermatologic Clinics·Medhat A El-MoftyMona R E Abdel-Halim
Dec 25, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Sara GandiniCarmelo Francesco Melchi
Apr 11, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·A PapakonstantinouE Lazaridou
May 3, 2006·International Journal of Dermatology·Konstantinos LasithiotakisAndroniki Tosca
Aug 14, 2019·Pigment Cell & Melanoma Research·Alessia ViscontiMario Falchi
Dec 13, 2017·Oncotarget·Alejandro Martin-GorgojoEduardo Nagore
Aug 18, 2004·Revista de saúde pública·Sonia R P de SouzaJosé M P de Souza
Apr 4, 2019·The Australasian Journal of Dermatology·Ayelet RishponMichael A Marchetti
Nov 22, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·A Buendía-EismanS Serrano-Ortega
Jun 1, 2016·Melanoma Management·Mehul BhattHooman Khorasani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Investigative Dermatology
Giorgia RandiOncology Study Group of the Italian Group for Epidemiologic Research in Dermatology (GISED)
Archives of Dermatology
Jean-Luc BulliardFabio Levi
© 2021 Meta ULC. All rights reserved