Melanogenesis in dermal melanocytes of Japanese Silky chicken embryos

Tissue & Cell
Claudia Ortolani-MachadoCloris Faraco

Abstract

The Japanese Silky chicken (SK) shows dermal and visceral hyperpigmentation. This study characterizes ultrastructurally the melanin granules developing in dermal melanocytes of the dorsal skin of SK, in an attempt to better understand the processes of melanogenesis in these permanently ectopic cells. The steps of melanogenesis are similar to those described for epidermal melanocytes, with melanosomes going from stage I to IV but, in SK, the maturation occurs in the cell body, as well as in the cytoplasmic processes. At stage III, the deposition of melanin is cumulative and can aggregate in rounded structures, which combine to turn into the mature granule. The final destiny of mature melanosomes is still unclear, although it was observed that dermal macrophages can accumulate melanin granules in their phagosomes. Even with the close proximity between melanocytes and other dermal cells, the transference of melanosomes was not observed. Our findings indicate that melanogenesis in dermal melanocytes in SK has the same morphological characteristics found in epidermal melanocytes, but the functional aspect still remains to be elucidated.

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Citations

Aug 2, 2011·Micron : the International Research and Review Journal for Microscopy·M H Amiri, Huda M Shaheen
Aug 21, 2015·Proceedings. Biological Sciences·Johan LindgrenBenjamin P Kear
Jan 13, 2009·Tissue & Cell·C F Ortolani-MachadoC D Faraco
May 6, 2020·Animals : an Open Access Journal From MDPI·Korakot NganvongpanitSupamit Mekchay

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