PMID: 15374244Mar 1, 1995Paper

Melatonin is an efficient antioxidant

Archives of Gerontology and Geriatrics
C PieriR Recchioni

Abstract

We have compared the peroxyl radical scavenger ability of melatonin with that of vitamin E, ascorbic acid (As.A.), reduced glutathione (GSH) and mannitol. All the antioxidants, except mannitol, prevented the lysis of human erythrocytes exposed to an azo-initiator of peroxyl radicals (2,2'-azo-bis(2-amidinopropane)dihydrochloride) at 37 degrees C. The percentage of this inhibition of erythrocyte lysis varied with the concentration of antioxidants, but the efficiency was melatonin > vitamin E > As.A. > GSH. Based on the assumption that each molecule of vitamin E scavenges two peroxyl radicals, the scavenging capacity of melatonin was four peroxyl radicals/molecule.

References

Jan 1, 1992·The International Journal of Neuroscience·R Sandyk
Nov 1, 1992·Comparative Biochemistry and Physiology. Comparative Physiology·C PieriF Marcheselli
Mar 1, 1992·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·R J Reiter
Jun 1, 1991·Aging : Clinical and Experimental Research·G P TrentiniM Criscuolo
Sep 1, 1985·Journal of Neurosurgery·S S Erlich, M L Apuzzo
Aug 1, 1987·Medical Hypotheses·R RozencwaigJ Ochoa
Feb 1, 1989·Biological Psychiatry·D R Thomas, A Miles
Jul 1, 1987·Chemistry and Physics of Lipids·E Niki
Jan 1, 1988·Annals of the New York Academy of Sciences·G J MaestroniW Pierpaoli
Nov 1, 1986·Biological Reviews of the Cambridge Philosophical Society·A M Holehan, B J Merry
Jun 30, 1987·Biochemical and Biophysical Research Communications·S Laganiere, B P Yu
Feb 15, 1983·Archives of Biochemistry and Biophysics·G W BurtonK U Ingold
Dec 19, 1980·Science·R J ReiterD T Dinh
May 1, 1993·Journal of Pineal Research·B PoeggelerL C Manchester
Jan 1, 1994·Life Sciences·S Saarela, R J Reiter
Jan 18, 1994·Proceedings of the National Academy of Sciences of the United States of America·W Pierpaoli, W Regelson
Mar 1, 1993·Free Radical Biology & Medicine·G CaoR G Cutler
Jan 1, 1992·Archives of Gerontology and Geriatrics·C PieriG Lupidi

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Citations

Nov 4, 2000·Journal of Biomedical Science·R J ReiterE Gitto
Mar 30, 1999·Biulleten' eksperimental'noĭ biologii i meditsiny·D M Izmaĭlov, L K Obukhova
Apr 25, 2007·Journal of Physiology and Biochemistry·C F Reyes-TosoD P Cardinali
Oct 1, 1995·Aging : Clinical and Experimental Research·B P Yu
Sep 11, 2007·Bioscience Reports·Deepa S MaharajSanty Daya
Mar 25, 1996·Molecular and Cellular Endocrinology·E SewerynekW M Daniels
Jan 1, 1996·Free Radical Biology & Medicine·K A MarshallB Halliwell
Jan 1, 1997·Life Sciences·E GiladC Szabó
Jun 5, 2002·Mechanisms of Ageing and Development·Russel J ReiterSusanne Burkhardt
Apr 1, 1999·Mechanisms of Ageing and Development·D M Izmaylov, L K Obukhova
Nov 27, 1999·Mechanisms of Ageing and Development·R J ReiterV Rouvier-Garay
Oct 14, 1998·Progress in Neurobiology·R J Reiter
Dec 25, 2002·Free Radical Biology & Medicine·Grant FowlerKeith U Ingold
Jan 16, 1999·Free Radical Biology & Medicine·F AntunesF Xi
Sep 21, 2000·Proceedings of the Society for Experimental Biology and Medicine·M Karbownik, R J Reiter
Jul 24, 2010·Antioxidants & Redox Signaling·Cynthia A Massaad, Eric Klann
Nov 1, 1996·Journal of Pineal Research·L C Ellis
Mar 24, 1998·Journal of Pineal Research·R PähklaL Rägo
Feb 3, 1999·Annals of the New York Academy of Sciences·R J ReiterD Acuña-Castroviejo
Jun 14, 2003·Redox Report : Communications in Free Radical Research·Dominique Bonnefont-RousselotMonique Gardès-Albert
Dec 5, 2008·Journal of Pineal Research·Eloisa GittoRussel J Reiter
Jul 15, 2011·Journal of Pineal Research·Annia GalanoRussel J Reiter
Oct 7, 2005·Journal of Pineal Research·Carlos F Reyes-TosoDaniel P Cardinali
Jun 28, 2005·Journal of Pineal Research·J MekhloufiM Gardès-Albert
Sep 3, 2009·Annals of the New York Academy of Sciences·Silvia CristofanonMarc Diederich
May 12, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Salvatore AversaEloisa Gitto
Aug 28, 2014·Molecular Neurobiology·Neeraj JoshiSarika Singh
May 9, 2012·Neuroscience Letters·Shilpa Chakravarty, Syed Ibrahim Rizvi
Apr 13, 1999·Biochemical and Biophysical Research Communications·S M DellegarG H Purser
Oct 25, 2002·The Journal of Pharmacy and Pharmacology·Russel J ReiterSilvia Lopez-Burillo
Oct 1, 2010·Current Therapeutic Research, Clinical and Experimental·Babak RezvanjooMorteza Samini
May 16, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology· VijayalaxmiTerence S Herman
Jun 14, 2005·World Journal of Surgery·Edward RamZeev Dreznik

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