PMID: 639825Apr 1, 1978Paper

Membrane lipid metabolism in Acholeplasma laidlawii A EF 22. Influence of cholesterol and temperature shift-down on incorporation of fatty acids and synthesis of membrane lipid species

European Journal of Biochemistry
A Christiansson, Ake Wieslander

Abstract

1. Membrane lipid metabolism in Acholeplasma laidlowii A EF 22 has been studied under different conditions by applying three different techniques for changing membrane viscosity: fatty acid and cholesterol supplementation and temperature changes. 2. The molar relationship between the two dominating membrane lipids, monoglucosyldiglyceride and diglucosyldiglyceride, is to a large extent determined by membrane viscosity properties. This is shown by the varying metabolic responses occurring during incorporation of different fatty acids with and without cholesterol and by temperature shift-down experiments. Higher viscosity in membranes stimulates synthesis of monoglucosyldiglyceride at the expense of diglucosyldiglyceride. Synthesis of phospho and phosphoglucolipids is affected as well. 3. Temperature shift-down from 37 degrees C to 17 degrees C results in an immediate synthesis of monoglucosyldiglyceride accompanied by an increased incorporation of unsaturated fatty acids into this lipid. Synthesis of the other membrane lipid species (containing more unsaturated fatty acids) lags behind temporarily. 4. Incorporation from an equimolar mixture of palmitic and oleic acids together with cholesterol yields greater amounts of oleic aci...Continue Reading

References

Apr 10, 1975·Nature·E Carlemalm, A Wieslander
Feb 25, 1977·Science·J E Rothman, J Lenard
Feb 14, 1977·Biochimica Et Biophysica Acta·R A DemelL L van Deenen
Apr 1, 1977·Biochimica Et Biophysica Acta·D L Melchior, J M Steim
Apr 18, 1977·Biochimica Et Biophysica Acta·A Wieslander, L Rilfors
Mar 25, 1975·Biochimica Et Biophysica Acta·A Helenius, K Simons
Jun 3, 1969·Biochimica Et Biophysica Acta·I Kahane, S Razin
May 1, 1971·Journal of Bacteriology·M Sinensky
Feb 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·M Sinensky
Jan 1, 1974·Digestion·B ArnesjöE Stahl
Jan 21, 1969·Biochimica Et Biophysica Acta·H Okuyama
Feb 2, 1971·Biochimica Et Biophysica Acta·L M van GoldeL L van Deenen
Sep 1, 1972·Biochimica Et Biophysica Acta·M B Abramson, D Pisetsky
Aug 1, 1971·Australian Veterinary Journal·J MarleyD A Watt
Jan 1, 1970·Journal of Bacteriology·R N McElhaney, M E Tourtellotte

❮ Previous
Next ❯

Citations

Jan 29, 2008·Journal of Fluorescence·Laure Burel-DeschampsPhilippe Giamarchi
Aug 14, 1992·Biochemical and Biophysical Research Communications·J W ChenF Huang
Jan 1, 1988·Critical Reviews in Microbiology·J Maniloff
Jun 24, 1987·Biochimica Et Biophysica Acta·W Curatolo
Jun 14, 1982·Biochimica Et Biophysica Acta·H C JarrellI C Smith
Jan 27, 1984·Biochimica Et Biophysica Acta·R N McElhaney
May 27, 1980·Biochimica Et Biophysica Acta·S Rottem
Mar 23, 1992·Biochimica Et Biophysica Acta·A DahlqvistA Wieslander
Feb 1, 1987·Journal of Bacteriology·L RilforsA Wieslander

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.