Membrane-mediated aggregation of anisotropically curved nanoparticles

Faraday Discussions
Alexander D OlingerMohamed Laradji

Abstract

Using systematic numerical simulations, we study the self-assembly of elongated curved nanoparticles on lipid vesicles. Our simulations are based on molecular dynamics of a coarse-grained implicit-solvent model of self-assembled lipid membranes with a Langevin thermostat. Here we consider only the case wherein the nanoparticle-nanoparticle interaction is repulsive, only the concave surface of the nanoparticle interacts attractively with the lipid head groups and only the outer surface of the vesicle is exposed to the nanoparticles. Upon their adhesion on the vesicle, the curved nanoparticles generate local curvature on the membrane. The resulting nanoparticle-generated membrane curvature leads in turn to nanoparticle self-assembly into two main types of aggregates corresponding to chain aggregates at low adhesion strengths and aster aggregates at high adhesion strength. The chain-like aggregates are due to the fact that at low values of adhesion strength, the nanoparticles prefer to lie parallel to each other. As the adhesion strength is increased, a splay angle between the nanoparticles is induced with a magnitude that increases with increasing adhesion strength. The origin of the splay angles between the nanoparticles is show...Continue Reading

References

May 1, 1986·Physical Review A: General Physics·G S Grest, K Kremer
Aug 9, 2002·Proceedings of the National Academy of Sciences of the United States of America·Imma FernandezRichard G W Anderson
Sep 28, 2002·Nature·Marijn G J FordHarvey T McMahon
Oct 7, 2003·Annual Review of Biomedical Engineering·Jennifer L West, Naomi J Halas
Dec 3, 2003·Science·Brian J PeterHarvey T McMahon
Jul 21, 2005·Technology in Cancer Research & Treatment·K K Jain
Jul 7, 2007·The Journal of Chemical Physics·Michael J A Hore, Mohamed Laradji
Jan 1, 2008·Small·Nastassja LewinskiRebekah Drezek
Jan 22, 2008·The Journal of Chemical Physics·Joel D RevaleeP B Sunil Kumar
Mar 11, 2008·Cell·Adam FrostVinzenz M Unger
May 1, 2009·Nano Letters·Andreas UngerMaximilian Kreiter
Jul 15, 2009·Journal of Structural Biology·Olivier Le BihanOlivier Lambert
Dec 8, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Subramanian Tamil SelvanNikhil R Jana
Dec 17, 2010·Angewandte Chemie·Zhongwei NiuQian Wang
Nov 4, 2011·Nano Letters·Robert VáchaDaan Frenkel
May 1, 2012·Physical Review Letters·Anđela Sarić, Angelo Cacciuto
Jul 19, 2012·The Journal of Physical Chemistry. B·Teresa Ruiz-HerreroMichael F Hagan
Jan 5, 2014·Nano Letters·Sabyasachi DasguptaGerhard Gompper
Dec 23, 2014·Soft Matter·Xin Yi, Huajian Gao

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Citations

Mar 1, 2018·Annual Review of Physical Chemistry·Thomas R Weikl
Jun 2, 2018·Soft Matter·Eric J SpanglerMohamed Laradji
Apr 25, 2020·Nanoscale·Enrico LavagnaLuca Monticelli
Mar 17, 2020·The Journal of Chemical Physics·Eric J Spangler, Mohamed Laradji
Aug 6, 2016·Soft Matter·Surya K GhoshRalf Metzler
May 14, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Sarah E Zuraw-WestonAnthony D Dinsmore
Jul 10, 2021·The Journal of Chemical Physics·Eric J Spangler, Mohamed Laradji
Dec 28, 2017·Nano Letters·Amir Houshang Bahrami, Thomas R Weikl
Jan 4, 2018·ACS Central Science·Mijo SimunovicGregory A Voth

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