Membrane-Mediated Cooperativity of Proteins

Annual Review of Physical Chemistry
Thomas R Weikl

Abstract

Besides direct protein-protein interactions, indirect interactions mediated by membranes play an important role for the assembly and cooperative function of proteins in membrane shaping and adhesion. The intricate shapes of biological membranes are generated by proteins that locally induce membrane curvature. Indirect curvature-mediated interactions between these proteins arise because the proteins jointly affect the bending energy of the membranes. These curvature-mediated interactions are attractive for crescent-shaped proteins and are a driving force in the assembly of the proteins during membrane tubulation. Membrane adhesion results from the binding of receptor and ligand proteins that are anchored in the apposing membranes. The binding of these proteins strongly depends on nanoscale shape fluctuations of the membranes, leading to a fluctuation-mediated binding cooperativity. A length mismatch between receptor-ligand complexes in membrane adhesion zones causes repulsive curvature-mediated interactions that are a driving force for the length-based segregation of proteins during membrane adhesion.

References

Jun 22, 1988·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·M DemboD Hammer
Nov 1, 1973·Zeitschrift Für Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie·W Helfrich
Aug 1, 1994·Biophysical Journal·R BruinsmaP Pincus
Nov 25, 1997·Biophysical Journal·T Sintes, A Baumgärtner
Oct 28, 1998·Biophysical Journal·K S KimG Oster
Oct 1, 1995·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·R R Netz, P Pincus
Dec 1, 1996·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·R GolestanianM Kardar
Jun 9, 1986·Physical Review Letters·R Lipowsky, S Leibler
Dec 28, 1999·Proceedings of the National Academy of Sciences of the United States of America·D M DavisJ L Strominger
Nov 23, 2000·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·K S KimG Oster
Nov 23, 2000·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·T R WeiklR Lipowsky
May 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·S Y QiA K Chakraborty
May 25, 2001·Nature·F D BatistaM S Neuberger
Jul 20, 2001·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·T R Weikl, R Lipowsky
Sep 27, 2002·Biophysical Journal·Nigel John Burroughs, Christoph Wülfing
Jan 7, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Thomas R Weikl
May 6, 2003·Biochimica Et Biophysica Acta·A G Lee
Dec 3, 2003·Science·Brian J PeterHarvey T McMahon
Dec 20, 2003·Physical Review Letters·Subhadip RaychaudhuriMehran Kardar
May 18, 2004·Trends in Immunology·Daniel M Davis, Michael L Dustin
Sep 21, 2004·Biophysical Journal·Thomas R Weikl, Reinhard Lipowsky
Nov 19, 2005·Science·Kaspar D MossmanMichael L Dustin
Dec 21, 2005·Nature Reviews. Molecular Cell Biology·Joshua Zimmerberg, Michael M Kozlov
Oct 3, 2006·Biophysical Journal·Ana Vitória BotelhoMichael F Brown
Dec 13, 2006·Physical Review Letters·Gabriel PopescuMichael S Feld
Feb 1, 2007·Annual Review of Biophysics and Biomolecular Structure·Olaf S Andersen, Roger E Koeppe
Feb 28, 2007·Biophysical Journal·Gary S AytonGregory A Voth
Mar 27, 2007·Biophysical Journal·Philippos K TsourkasSubhadip Raychaudhuri
Apr 3, 2007·PLoS Computational Biology·Benjamin A Shoemaker, Anna R Panchenko
May 8, 2007·PLoS Computational Biology·Tristan UrsellRob Phillips
Jul 31, 2007·Journal of the American Chemical Society·Xavier PerioleThomas P Sakmar
Feb 1, 2008·Biophysical Journal·Anne PierresPierre Bongrand
Mar 11, 2008·Cell·Adam FrostVinzenz M Unger
Jun 3, 2008·Biophysical Journal·Felix CampeloMichael M Kozlov
Oct 7, 2008·Biophysical Journal·Beate WestFriederike Schmid
Oct 15, 2008·Physical Review Letters·Ulrich SchmidtMatthias Weiss
May 6, 2009·Biophysical Journal·Erdinç Atilgan, Ben Ovryn
May 22, 2009·Nature·Rob PhillipsPierre Sens
Sep 1, 2009·Proceedings of the National Academy of Sciences of the United States of America·Timo BetzCécile Sykes
Nov 13, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Thorsten Auth, Gerhard Gompper

❮ Previous
Next ❯

Citations

May 10, 2019·Soft Matter·Osman Kahraman, Christoph A Haselwandter
May 3, 2019·Nanotechnology·Arash Bahrami, Amir Houshang Bahrami
Jun 13, 2019·The Journal of Membrane Biology·T DevanandSatyavani Vemparala
Oct 27, 2018·Biomolecules·Haleh Alimohamadi, Padmini Rangamani
Nov 9, 2019·Physical Review Letters·Andriy Goychuk, Erwin Frey
Nov 21, 2020·Physical Review. E·Mingyuan Ma, Christoph A Haselwandter
Jul 31, 2021·Applied Sciences·Samuel Botterbusch, Tobias Baumgart
Sep 21, 2019·Nano Letters·Erik B WatkinsLudger Johannes
Oct 23, 2021·The Journal of Physical Chemistry Letters·Mohsen Sadeghi, Frank Noé
Dec 7, 2021·Journal of Chemical Theory and Computation·Tongwei ChenHaojun Liang
Dec 18, 2021·Nature Chemical Biology·Jinghua GeYongli Zhang

❮ Previous
Next ❯

Methods Mentioned

BETA
electron
electron tomography
fluorescence microscopy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annual Review of Physical Chemistry
Nicholas A MoringoChristy F Landes
Annual Review of Physical Chemistry
Stewart A MalloryAngelo Cacciuto
Annual Review of Physical Chemistry
K L Dimuthu M WeerawardeneChristine M Aikens
© 2022 Meta ULC. All rights reserved