PMID: 7017710Jan 1, 1981Paper

Membrane potential changes during the first steps of coliphage infection

Proceedings of the National Academy of Sciences of the United States of America
B Labedan, L Letellier

Abstract

Immediately after adsorption, phages T4 and T5 induce a partial depolarization of the host cytoplasmic membrane. Infected bacteria respond to this phage-induced effect by a repolarization that leads to a new steady state of reduced membrane potential. The rate and extent of repolarization are adjusted to the intensity of depolarization, which depends on the number of adsorbed phages. Consequently, the new steady state membrane potential is attained in the same interval of time regardless of the maximum depolarization. These membrane potential changes appear to be independent of phage-specific properties (type of phage, presence of DNA and internal proteins, injection process) and of several membrane-related parameters (temperature, external pH, preinfectious level of membrane potential). We propose that phage adsorption to the outer membrane triggers the emission of a signal that is transmitted to the cytoplasmic membrane. Additivity of independent signals is possible when stimuli (phages) are added at the same time. Additional adsorption of phages has no further depolarizing effect as soon as the repolarization begins. We propose that this refractoriness to secondary depolarization nd the shut-off of the first depolarization a...Continue Reading

References

Sep 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·H TherisodE Shechter
Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·B Labedan, E B Goldberg
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Citations

Feb 1, 1984·Journal of Bioenergetics and Biomembranes·B Labedan, L Letellier
Sep 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·M E Bayer, M H Bayer
Feb 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J P BourdineaudL Letellier
May 1, 2007·Journal of Bacteriology·Gillian L Ryan, Andrew D Rutenberg
Sep 11, 2007·Journal of Bacteriology·Taehyun ParkRy Young
Mar 7, 2008·Microbiology and Molecular Biology Reviews : MMBR·Kelly C Rice, Kenneth W Bayles
Jul 19, 2001·Proceedings of the National Academy of Sciences of the United States of America·A GründlingR Young
Dec 14, 2011·Virology·Lina JakutytėRimantas Daugelavičius
Apr 17, 2013·Biotechnology and Applied Biochemistry·Appaiah Chemira BiddappaSriram Padmanabhan
Nov 28, 2012·Advanced Healthcare Materials·Wenjuan ZhuangJingbo Liu
Sep 24, 2019·Molecular Microbiology·Lynn C ThomasonDonald L Court
Apr 1, 1995·European Journal of Biochemistry·M BonhiversL Letellier
Jan 1, 1983·Journal of Bacteriology·A Filali Maltouf, B Labedan
Dec 1, 1982·Journal of Bacteriology·D B Wilson, A Okabe
Jun 1, 1984·Journal of Virology·C Hulen, J Legault-Demare
Aug 1, 1997·Journal of Bacteriology·R DaugelaviciusD H Bamford
Jan 1, 1991·Journal of Bacteriology·M E Bayer, M H Bayer

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