PMID: 9429984Jan 1, 1997Paper

Membrane properties of mouse dorsal cochlear nucleus neurons in vitro

Journal of Basic and Clinical Physiology and Pharmacology
E AğarD J Sanders

Abstract

Intracellular recordings were made from neurons of the mouse dorsal cochlear nucleus (DCN) in vitro using current clamp techniques in the presence or absence of different ion channel blocking drugs. Four electrophysiologically distinct cell groups were identified in the DCN. The groups were characterized on the basis of their spontaneous firing properties, the shape of the action potential (AP) and the pattern of firing, the shape of the current-voltage (I/V) relationship and the effects of channel blocking agents. By comparison with known histology, three of the four DCN groups were postulated to be cartwheel-like, fusiform-like, or tuberculoventral-like cells. The fourth group was postulated to be a stellate-like as it had similar properties to the spike train (stellate) cell of the AVCN. DCN stellate-like cells were spontaneously active, the action potentials (APs) were always followed by a large, brief hyperpolarization and the cells had linear current voltage relationships. The fusiform-like cells were spontaneously active and spontaneous IPSPs were also observed. The I/V relationship was linear for these cells. Tuberculoventral-like cells were not spontaneously active, but APs could be elicited by inward current injection...Continue Reading

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Jan 1, 1996·Journal of Basic and Clinical Physiology and Pharmacology·E AğarD J Sanders
Jan 1, 1996·Journal of Basic and Clinical Physiology and Pharmacology·E AĝarD J Sanders

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Citations

Jan 3, 2006·Brain Research·Paul G Finlayson, James A Kaltenbach
Dec 20, 2002·Acta Physiologica Hungarica·G Szucs, Z Rusznák

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