Membrane trafficking in morphogenesis and planar polarity

Traffic
Yi XieJ Todd Blankenship

Abstract

Our understanding of how membrane trafficking pathways function to direct morphogenetic movements and the planar polarization of developing tissues is a new and emerging field. While a central focus of developmental biology has been on how protein asymmetries and cytoskeletal force generation direct cell shaping, the role of membrane trafficking in these processes has been less clear. Here, we review recent advances in Drosophila and vertebrate systems in our understanding of how trafficking events are coordinated with planar cytoskeletal function to drive lasting changes in cell and tissue topologies. We additionally explore the function of trafficking pathways in guiding the complex interactions that initiate and maintain core PCP (planar cell polarity) asymmetries and drive the generation of systematically oriented cellular projections during development.

References

Oct 1, 1984·Developmental Biology·G C Schoenwolf, M V Franks
Jan 23, 1996·Proceedings of the National Academy of Sciences of the United States of America·M MilánA García-Bellido
Oct 15, 1996·Proceedings of the National Academy of Sciences of the United States of America·M MilánA García-Bellido
Dec 29, 2000·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·R KellerP Skoglund
Nov 9, 2001·Annual Review of Genetics·U TepassR Fehon
May 23, 2002·Developmental Cell·Paul N Adler
Jun 14, 2002·Developmental Cell·John B WallingfordRichard M Harland
Jul 26, 2002·Seminars in Cell & Developmental Biology·David R P TreeJeffrey D Axelrod
Apr 16, 2003·Differentiation; Research in Biological Diversity·Ray KellerDavid R Shook
Nov 19, 2003·Mechanisms of Development·Suzanne Eaton
Nov 19, 2003·Mechanisms of Development·David Shook, Ray Keller
Mar 20, 2004·Developmental Cell·Jennifer A Zallen, Eric Wieschaus
Jan 22, 2005·Trends in Genetics : TIG·Kelly K Nikolaidou, Kathy Barrett
Mar 5, 2005·The Journal of Biological Chemistry·Suzanne R Pfeffer
Mar 31, 2005·Current Biology : CB·Lilianna Solnica-Krezel
Oct 4, 2005·Developmental Cell·Florian UlrichCarl-Philipp Heisenberg
Dec 6, 2005·Developmental Cell·Anne-Kathrin ClassenSuzanne Eaton
Aug 3, 2006·Proceedings of the National Academy of Sciences of the United States of America·Bianka L GrosshansPeter Novick
Oct 3, 2006·Developmental Cell·J Todd BlankenshipJennifer A Zallen
Oct 19, 2006·Developmental Biology·David Strutt, Helen Strutt
Jun 19, 2007·Cell·Jennifer A Zallen
Jul 25, 2007·The Journal of Cell Biology·Shin-Ichiro YoshimuraFrancis A Barr
Aug 19, 2007·Journal of Cell Science·J Todd BlankenshipJennifer A Zallen
Mar 18, 2008·Seminars in Cell & Developmental Biology·Jennifer A Zallen, J Todd Blankenship
Aug 20, 2008·Annual Review of Genetics·Matias Simons, Marek Mlodzik
Nov 4, 2008·Nature Cell Biology·Matteo RauziPierre-François Lenne
Nov 26, 2008·Nature·Adam C MartinEric F Wieschaus
Aug 12, 2009·Seminars in Cell & Developmental Biology·Jeffrey D Axelrod
Oct 10, 2009·Journal of Biomechanics·Lance A DavidsonJian Zhou
Jan 26, 2010·Current Biology : CB·Jen-Yi Lee, Richard M Harland

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Citations

Dec 31, 2019·Developmental Cell·Kate E CavanaughMargaret L Gardel
Feb 3, 2021·Development·Véronique Van De BorStéphane Noselli
Apr 2, 2021·The EMBO Journal·Nicholas D Serra, Meera V Sundaram
Jun 3, 2021·Nature Reviews. Molecular Cell Biology·Sara SigismundPier Paolo Di Fiore

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