PMID: 18212428Jan 24, 2008Paper

Membranous Glomerulonephritis in a Patient Presenting with Chyluria, Probably due to Filariasis: How far should we investigate?

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
A R Al-Anazi

Abstract

A 38-years of Bangladeshi woman with a post medical history of treated Bancroftian Filariasis ten years before, presented with chyluria and heavy proteinuria. Percutaneous renal biopsy was consistent with membranous glomerulonephritis. The patient was treated with diethylcarbamazinc (DEC), and later, with azathioprine and prednisolone for the nephrosis. The chyluria disappeared with treatment, but recurred four months later, despite persistent drug therapy. The proteinuria dropped to 2.4 g and 0.2 g/24 hours at two and twelve weeks respectively. After two years of follow-up, the chyluria persisted but the proteinuria remained below 0.2g/24 hours, while plasma proteins remained within normal limits. The patient maintained stable body weight, good general health status, stable renal functions and normal lipid and hepatic profiles. The numerous investigations carried out to elucidate the etiology of the chyluria were not rewarding. The conservative approach for the management of chyuria adopted in this patient seems to be appropriate.

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
P S Williams, J M Bone
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
B Leaker, G H Neild
© 2021 Meta ULC. All rights reserved