Membranous glomerulopathy: emphasis on secondary forms and disease variants

Advances in Anatomic Pathology
Glen S Markowitz

Abstract

Membranous glomerulopathy (MGN) is characterized by subepithelial immune complex deposits and glomerular basement membrane (GBM) thickening. The majority of patients present with nephrotic syndrome and outcomes are variable. Pathologically, deposits at sites other than the subepithelial aspect of the GBM favor the presence of secondary forms of MGN which are seen most commonly in the setting of autoimmune disease, infection, neoplasia, and with certain therapeutic agents. MGN is the most common form of de novo glomerular disease seen in the renal allograft and may be seen concurrently with other forms of glomerular disease including focal segmental glomerulosclerosis, IgA nephropathy, diabetic nephropathy, and anti-TBM nephritis. This review emphasizes the detection of secondary forms and variants of MGN.

References

May 1, 1977·Kidney International·J W Eagen
Feb 1, 1992·Kidney International·S Wakai, A B Magil
Aug 1, 1991·Journal of the American Society of Nephrology : JASN·E L Ramos
Jul 1, 1990·Journal of the American Society of Nephrology : JASN·W G Couser
Aug 1, 1989·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·L TruongC L Pirani
Dec 1, 1974·The American Journal of Medicine·W G CouserE J Lewis
Sep 1, 1983·Kidney International·J C JennetteF G Dalldorf
May 1, 1984·Clinical Immunology and Immunopathology·E PetterssonA Miettinen
Dec 1, 1980·The American Journal of Medicine·F LlachS G Massry
Jul 7, 1995·The Journal of Biological Chemistry·T R NelsonR J Butkowski
May 1, 1995·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·G S MarkowitzV W Folkert
Feb 1, 1994·The American Journal of Surgical Pathology·F M LaiP K Li
Jul 1, 1993·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·D M BursteinM M Schwartz
May 1, 1997·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·W Y TseJ Michael
Dec 31, 1997·The Journal of Clinical Investigation·D KerjaschkiR A Orlando
Oct 17, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M B Stokes, C E Alpers
Jan 13, 1999·Nephron·K NakazawaH Shigematsu
Jun 16, 1999·Kidney International. Supplement·N Muirhead
Jul 13, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·G S MarkowitzV D D'Agati
Feb 29, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·P RuggenentiG Remuzzi
Mar 4, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·F M LaiK N Lai
Aug 3, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·N KambhamV D D'Agati

❮ Previous
Next ❯

Citations

Aug 2, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·L Nicholas CosseyChris P Larsen
Dec 1, 2012·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Christopher P LarsenPatrick D Walker
Feb 26, 2016·Chinese Medical Journal·Ming-Hua ShangXue-Guang Liu
Feb 1, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Fernando C FervenzaUlrich Specks
Feb 11, 2015·Clinical Journal of the American Society of Nephrology : CJASN·Andrew S BombackMichael J Choi
Feb 6, 2016·The American Journal of Surgical Pathology·Jessica HemmingerTibor Nadasdy
Jan 23, 2019·Kidney International·Shane A BobartFernando C Fervenza
Oct 2, 2021·Nature Reviews. Disease Primers·Pierre RoncoJack Wetzels

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Ultrastructural Pathology
M AkhtarS Al-Mohaya
Clinical Journal of the American Society of Nephrology : CJASN
Richard J Glassock
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
Patrick D WalkerAd Hoc Committee on Renal Biopsy Guidelines of the Renal Pathology Society
Advances in Chronic Kidney Disease
Paul E Segal, Michael J Choi
© 2021 Meta ULC. All rights reserved