Memory and midazolam conscious sedation

British Dental Journal
G Nadin, P Coulthard

Abstract

To investigate the degree of amnesia seen in patients undergoing minor oral surgery with intravenous midazolam sedation. Hospital out-patients in the UK in 1995-6. 24 patients undergoing minor oral surgery procedures under local anaesthetic, with or without midazolam sedation, as determined by clinical need. Picture cards were shown to patients before and during the procedure. Post-operatively, before discharge and 1 week later, the patients were questioned about their memory of both the pictures and procedure. The sedated group demonstrated more amnesia for the pictures shown after the start of treatment, but their memory of the pretreatment pictures was initially better than that of the non-sedated patients. The non-sedated patients exhibited no memory loss for the surgical procedure. Recall of the surgery was very variable among the sedated patients, from some remembering all aspects, to others with no recollection after the venepuncture. Overall, the sedated patients exhibited significantly greater amnesia for the surgical procedure. The degree of amnesia in the sedated group was also investigated with respect to pretreatment anxiety levels, sedation level achieved and the dose of midazolam administered. The first two varia...Continue Reading

Citations

May 4, 2004·The British Journal of Oral & Maxillofacial Surgery·Zuhal Küçükyavuz, Mine Cambazoğlu
Feb 28, 2001·Australian Dental Journal·J P RogersA E Gale
Feb 2, 2006·The Journal of Oral Implantology·Gintaras JuodzbalysRicardas Kubilius
Nov 21, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Paul G SimsDavid W Todd
Jan 13, 2005·Anaesthesia·G Lahoud
Apr 14, 1999·The American Journal of Gastroenterology·D D ProctorE M Christie
Oct 24, 2002·British Journal of Anaesthesia·L PainP Oberling
May 3, 2019·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Teresita FerraryBetina Orman
Nov 24, 2019·British Dental Journal·Aliya Hasan, Valmiki Sharma
May 27, 2021·International Journal of Clinical Practice·Hye-Min SohnJung-Won Hwang

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