Memory impairment and Benign Epilepsy with centrotemporal spike (BECTS): a growing suspicion

Brain and Cognition
Alberto VerrottiGiuseppe Gobbi

Abstract

Benign Epilepsy with centrotemporal spikes (BECTS) is considered a benign type of epilepsy; nevertheless a significant number of children present clear and heterogeneous cognitive deficits such as memory disturbances. Thus far, evidence about memory impairment has been less than conclusive. To clarify the quality of memory functioning in BECTS children, an analysis of existing findings has been conducted trying to identify the type of memory deficits and their underlying factors. Short- and long-term declarative memory are impaired in BECTS children, with both verbal and non-verbal material; co-occurrence of attentional, linguistic and behavioral disturbances is reported. In children with continuous spikes and waves during the slow-wave sleep pattern the normal downscaling of slow-wave activity is absent, disrupting plastic brain processes of sleep-related memory consolidation. In BECTS children, NREM sleep interictal epileptiform discharges (IED) may interfere in the dialogue between temporal and frontal cortex, causing declarative memory deficits: the role of NREM sleep IED acquires a special importance, leading to methodological guidance and suggesting aims for future researches in the field of childhood neuroscience.

References

Jun 1, 1990·Italian Journal of Neurological Sciences·P D'AlessandroA Testa
Jun 25, 1982·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·T Shallice
Mar 1, 1984·Brain : a Journal of Neurology·J H AartsA J Wilkins
Nov 12, 1998·Neuropediatrics·U StadenB G Neville
Nov 27, 1999·Developmental Neuroscience·M N Metz-LutzC Marescaux
Jan 5, 2000·Developmental Medicine and Child Neurology·C CroonaK E Eeg-Olofsson
Oct 6, 2000·Pediatric Neurology·M H Kohrman, P R Carney
Oct 18, 2000·Developmental Medicine and Child Neurology·T DeonnaE Roulet
Apr 23, 2003·Journal of Experimental Child Psychology·Darlene DeMarie, John Ferron
Oct 1, 1955·Journal of Consulting Psychology·R M REITAN
Jan 1, 1994·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·M W OttoJ F Rosenbaum
Dec 12, 2003·Developmental Medicine and Child Neurology·Claire Mayor DuboisThierry Deonna
Oct 7, 2004·Neurobiology of Learning and Memory·Russell A Poldrack, Paul Rodriguez
Dec 8, 2004·Epilepsy & Behavior : E&B·Sa LindgrenOrvar Eeg-Olofsson
Dec 27, 2005·Sleep Medicine Reviews·Giulio Tononi, Chiara Cirelli
Nov 16, 2006·Epilepsia·Marie-Noëlle Metz-Lutz, Melissa Filippini
Jun 26, 2007·Archives of Disease in Childhood·Catherine M HillAnnette Karmiloff-Smith
Dec 11, 2007·Nature Neuroscience·Fiona McNab, Torkel Klingberg
Mar 3, 2009·Sleep Medicine Reviews·Susanne DiekelmannJan Born
Jan 26, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Oliviero BruniRaffaele Ferri
Jul 6, 2010·Brain & Development·Giuseppe CapovillaDario Pruna
Mar 29, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Bigna K BölsterliReto Huber
Jul 20, 2011·Epilepsy & Behavior : E&B·Joost Nicolai, Dorothée Kasteleijn-Nolst Trenité
Aug 30, 2011·Epilepsy & Behavior : E&B·Charline UrbainPatrick Van Bogaert
Jan 10, 2012·Epilepsia·Anna B SmithDeb K Pal
Mar 15, 2012·Neuroscience and Biobehavioral Reviews·Noa Ofen
Mar 21, 2012·Neuroscience and Biobehavioral Reviews·I WilhelmJ Born
Jul 4, 2012·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·S EbusB Aldenkamp
Jul 21, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Noa OfenJohn D E Gabrieli
Sep 11, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Pasquale ParisiAlberto Verrotti

❮ Previous
Next ❯

Citations

Jul 22, 2015·Expert Review of Neurotherapeutics·Huan LiaoXuefeng Wang
Mar 18, 2015·Epilepsy & Behavior : E&B·Jennifer VannestTracy A Glauser
Dec 30, 2014·Epilepsy & Behavior : E&B·Sophie GalerPatrick Van Bogaert
Jul 1, 2015·Frontiers in Human Neuroscience·Yvonne Höller, Eugen Trinka
May 20, 2015·Epilepsy Research·Fenglai XiaoDong Zhou
Nov 19, 2014·Sleep & Breathing = Schlaf & Atmung·Maria GogouEvaggelos Pavlou
Oct 27, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Kathryn E AthertonChristopher R Butler
Jan 28, 2015·Epilepsy & Behavior : E&B·Melanie A McNally, Eric H Kossoff
Jul 11, 2018·Acta Neurologica Scandinavica·Hisako FujiwaraJennifer Vannest
Mar 7, 2020·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Fiona M BaumerRobert S Fisher
Apr 6, 2019·Journal of Speech, Language, and Hearing Research : JSLHR·Silje SystadSolveig-Alma Halaas Lyster
Sep 29, 2020·Frontiers in Neurology·Péter Halász, Anna Szűcs
May 28, 2019·Frontiers in Neurology·Zeinab GharaylouMahmoudreza Hadjighassem
Feb 28, 2017·Frontiers in Neuroscience·Emilie Bourel-PonchelFabrice Wallois
Sep 26, 2020·Acta Neurologica Scandinavica·Liu-Cheng ChenLongshan Shen
Dec 27, 2019·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Patrick Van Bogaert
Jun 25, 2021·Frontiers in Human Neuroscience·Victoria GeorgopoulouMary H Kosmidis
Jul 13, 2021·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Inês Duarte Sá Seixas RamosAna Filipa Lopes
Aug 25, 2021·Epilepsy & Behavior : E&B·Martina Paola ZanaboniValentina De Giorgis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Benign Rolandic Epilepsy

Benign Rolandic epilepsy is a partial idiopathic epilepsy of childhood presenting with a nocturnal seizure and with a typical EEG showing centrotemporal spike and multifocal or generalized sharp slow waves. Here is the latest research.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.