Memory outcome following left anterior temporal lobectomy in patients with a failed Wada test

Epilepsy & Behavior : E&B
Chaturbhuj RathoreKurupath Radhakrishnan

Abstract

This study aimed to compare the memory outcome following left anterior temporal lobectomy (ATL) between patients with a failed Wada test and patients who passed the Wada test. From 1996 to 2002, we performed the Wada test on all patients with unilateral left mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) and concordant electroclinical data before ATL. We used a 12-item recognition paradigm for memory testing and awarded a score of +1 for each correct response and -0.5 for each incorrect response. No patient was denied surgery on the basis of Wada scores. We assessed cognitive and memory functions using the Wechsler Adult Intelligence Scale and the Wechsler Memory Scale preoperatively and at one year after ATL. We compared the number of patients who showed decline in memory scores, as per the published reliable change indices, between the patients with a failed Wada test and the patients who passed the Wada test. Out of the 116 eligible patients with left MTLE-HS, 88 underwent bilateral Wada test, while 28 underwent ipsilateral Wada test. None of them developed postoperative amnesia. Approximately, one-third of patients with a failed Wada memory test when the failure was defined as a contralateral score of <4...Continue Reading

References

Apr 21, 1998·Seizure : the Journal of the British Epilepsy Association·S Baxendale
Aug 30, 2000·Epilepsia·M B Rao, K Radhakrishnan
Aug 4, 2001·The New England Journal of Medicine·S WiebeUNKNOWN Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group
Mar 1, 2003·Epilepsy & Behavior : E&B·James R. WhiteRobert J. Gumnit
Jun 25, 2003·Brain : a Journal of Neurology·J JanszkyA Ebner
Oct 1, 1995·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·G J Chelune
Mar 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·M E LacruzR G Morris
May 18, 2004·Epilepsia·Heinz-Gregor Wieser, UNKNOWN ILAE Commission on Neurosurgery of Epilepsy
Sep 11, 2007·Epilepsia·Adele H HaberSelim R Benbadis
Jun 6, 2008·Seizure : the Journal of the British Epilepsy Association·Jayanthi ManiDudley Dinner
Jul 2, 2008·Epilepsy & Behavior : E&B·Tobias LoddenkemperGabriel Möddel
Sep 21, 2010·Epilepsy & Behavior : E&B·Jeffrey R Binder
Feb 9, 2012·Epilepsia·Lindsay A WhitmanChad Carlson
Mar 8, 2012·Journal of Neurology, Neurosurgery, and Psychiatry·Kathrin WagnerAndreas Schulze-Bonhage
Mar 8, 2012·JAMA : the Journal of the American Medical Association·Jerome EngelUNKNOWN Early Randomized Surgical Epilepsy Trial (ERSET) Study Group
Oct 15, 2013·Epilepsy Research·Chaturbhuj RathoreKurupath Radhakrishnan

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Citations

Dec 15, 2015·International Journal of Surgery·Urvashi ShahNeeraj Jain
May 3, 2019·Current Neurology and Neuroscience Reports·Andreu Massot-TarrúsSeyed M Mirsattari
Jun 30, 2019·Frontiers in Neurology·Rudolf KreidenhuberStefan Rampp

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