Menarche in type 1 diabetes is still delayed despite good metabolic control

Fertility and Sterility
Antonio PicardiPaolo Pozzilli

Abstract

To analyze the age at menarche of girls with type 1 diabetes (T1D) who were diagnosed with the disease before puberty and compare it with that of an age-matched group of normal girls. Previous studies on the appearance of menarche showed that the mean age of onset of menarche is delayed in girls affected by T1D compared with normal girls. Case-control study. Patients and controls in an academic research environment. We studied, retrospectively, the charts of 162 consecutive girls with T1D born in a geographically defined region between 1984 and 1994 with a mean disease duration of 3-5 years, all of whom were on intensive insulin therapy since diagnosis of T1D. The control group consisted of 214 normal girls born between 1984 and 1994, who agreed to fill in an anonymous questionnaire regarding age at menarche and other clinical information. There was no intervention per se in the study. Age at menarche appears as a dependent variable of body mass index (BMI), HbA1c, and so on. BMI, HbA1c, and duration of T1D at menarche were considered among the potential factors affecting the age of menarche. Age at menarche in girls with T1D was significantly delayed compared with control girls (12.6 +/- 1.5 years vs. 12.25 +/- 1.4 years, resp...Continue Reading

References

May 1, 1987·Endocrine Reviews·L Poretsky, M F Kalin
Jun 1, 1994·Diabetic Medicine : a Journal of the British Diabetic Association·C J AdcockD B Dunger
Mar 29, 2003·Diabetes Care·Elsa S StrotmeyerJanice S Dorman
Jun 27, 2006·Journal of Diabetes and Its Complications·Abdelaziz ElaminTorsten Tuvemo

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Citations

Jun 20, 2012·Human Reproduction Update·E CodnerM Tena-Sempere
May 10, 2011·Reproductive Biology and Endocrinology : RB&E·Bahareh M SchweigerGeorgeanna J Klingensmith
Nov 27, 2015·Diabetologia·Valma HarjutsaloUNKNOWN FinnDiane Study Group
Nov 30, 2013·Endocrinology and Metabolism Clinics of North America·Anindita Nandi, Leonid Poretsky
May 3, 2011·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Emilio García-GarcíaAntonio Bonillo
Dec 3, 2010·Fertility and Sterility·Ethel CodnerUNKNOWN Chilean Group for the Study of Ovarian Function in Type 1 Diabetes
Aug 13, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Anna DeltsidouChristos S Bartsocas
Oct 15, 2011·Pediatric Diabetes·Ethel CodnerPaulina M Merino
Mar 20, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Elena M MorariuMary T Korytkowski
Aug 21, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Oindrila RahaRaghavendra Rao Vadlamudi
Feb 24, 2015·Journal of Pediatric and Adolescent Gynecology·K C X PereiraM P Gama
Feb 21, 2019·Diabetic Medicine : a Journal of the British Diabetic Association·Y YiT Costacou
Oct 22, 2014·Menopause : the Journal of the North American Menopause Society·Tae-Hwa BaekHyun-Young Park
Apr 22, 2016·International Journal of Pediatric Endocrinology·Talia L BrownR Paul Wadwa
Jun 27, 2020·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Hongyuan JiangJohn D Wark

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