Ménétrier's disease in childhood: a case report from China.

BMC Pediatrics
Jiewei ZhangTing Zhang

Abstract

Ménétrier's disease (MD) is a protein-losing gastropathy characterized by gastric hypertrophy, foveolar hyperplasia and hypoalbuminemia. MD is uncommon in childhood with nonspecific clinical symptoms, and the exact cause of pediatric MD is still unclear. Here, we reported a 4 year and 10-month boy presenting with MD from China. The patient was suffered with vomiting, abdominal pain, hypoproteinemia and edema. Laboratory tests showed that the boy was infected with Clostridium difficile (CD). Gastrointestinal endoscopy revealed giant gastric folds, and histological gastric biopsies showed foveolar hyperplasia with glandular atrophy, infiltration of eosinophils in the lamina propria of the patient. Finally, the boy was recovered after supportive therapy with intravenous albumin and CD eradication. For the nonspecific clinical symptoms of MD, gastrointestinal endoscopic evaluations with gastric tissue biopsies are required to establish the diagnosis of MD in children with unexplained hypoalbuminemia.

References

Feb 1, 1992·Journal of Pediatric Gastroenterology and Nutrition·D Ben AmitaiB Z Garty
Dec 1, 1988·Annals of Surgery·T M SundtR A Malt
Jan 1, 1986·Gastrointestinal Radiology·A BakerR Moran
Aug 1, 1993·Journal of Pediatric Gastroenterology and Nutrition·R O OccenaR J Sokol
May 1, 1993·Gastroenterology·H C WolfsenN J Talley
Mar 1, 1997·European Journal of Pediatrics·M YamadaH Takita
May 29, 2007·Gastrointestinal Endoscopy·Dae Won JunYoung Sook Park
Jul 25, 2008·European Journal of Pediatrics·O Megged, Y Schlesinger
Jan 27, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Joseph FriedmanMichael Tyshkov
Oct 12, 2010·Gut·Amy RichRobert J Coffey
Jun 13, 2012·World Journal of Gastroenterology : WJG·Giovanni Di NardoSalvatore Cucchiara
Feb 15, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sahil KhannaDarrell S Pardi
Mar 22, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L Clifford McDonaldMark H Wilcox
Apr 8, 2019·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C TardC Jung

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Citations

Jan 29, 2021·Pediatric Gastroenterology, Hepatology & Nutrition·Jasmina KrikilionYvan Vandenplas

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Methods Mentioned

BETA
biopsy
surgical resection
biopsies

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