Meningioma: proliferating potential and clinicoradiological features

Neurosurgery
S NakasuJ Handa

Abstract

We examined the proliferative potentials of meningiomas in 120 patients using the MIB-1 antibody against the Ki-67 antigen and compared them with the clinicoradiological features. The Ki-67 staining index (SI) did not relate to the age and sex of the patients or the location of the tumors. Asymptomatic meningiomas showed significantly lower SIs (mean +/- standard deviation [SD], 0.87 +/- 0.56%) than symptomatic meningiomas (mean +/- SD, 1.63 +/- 2.17%). We found no relation between SIs and clinical symptoms and signs in the symptomatic meningiomas. A weak correlation was found between the size of tumors and Ki-67 SIs (r = 0.21; P = 0.024). There were significant differences in SIs between calcified (mean +/- SD, 0.77 +/- 0.41%) and noncalcified tumor (mean +/- SD, 1.75 +/- 2.25%). Diffusely calcified tumors (mean +/- SD, 0.57 +/- 0.34%) showed lower SIs than focally calcified tumors (mean +/- SD, 0.92 +/- 0.41%). Lobulated tumors showed higher SIs (mean +/- SD, 2.85 +/- 3.68%) than round tumors (mean +/- SD, 1.06 +/- 0.67%). Tumors with perifocal edema or unclear borders had higher SIs than did those without such features. Signal intensities on T1-weighted magnetic resonance images had no relation to SIs, whereas low-intensity ...Continue Reading

References

May 1, 1992·Journal of Computer Assisted Tomography·R D KaplanP C Johnson
Nov 1, 1989·Journal of Neurosurgery·M RohringerA A Sima
Mar 1, 1989·Radiology·A D ElsterJ C Contento
Jan 1, 1987·Acta Neuropathologica·W RoggendorfJ Peiffer
Nov 1, 1986·Radiology·M V SpagnoliR A Zimmerman
Apr 1, 1987·Surgical Neurology·S NakasuJ F Llena
Mar 1, 1986·Surgical Neurology·J JääskeläinenA Servo
Jan 1, 1970·Acta Neurologica Scandinavica·A RausingJ Stenflo
Jan 15, 1983·International Journal of Cancer. Journal International Du Cancer·J GerdesH Stein
Jun 1, 1983·Neurosurgery·J J GilbertD Malott
Jul 1, 1981·Archives of Neurology·S N Bellur, V Chandra
Jan 1, 1995·Journal of Neurosurgery·G A YounisJ M Bruner
Jan 1, 1993·Acta neurochirurgica·K G GoE L Mooyaart

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Citations

Dec 31, 1997·The American Journal of Surgical Pathology·A PerryC M Lohse
Oct 3, 1999·Journal of Neurosurgery·A Kanat, Y Aydin
Dec 21, 2007·Brain Tumor Pathology·Tetsuo HashibaToshiki Yoshimine
Jan 15, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Pierpaolo LunardiGiovanni Ghetti
Feb 14, 2012·Journal of Neuro-oncology·Yosuke KawaharaJun-Ichiro Hamada
Dec 13, 2016·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Jacob B HunterGeorge B Wanna
May 4, 2000·Journal of Neurosurgery·S NakasuM Matsuda
Mar 29, 2001·Neurosurgery·D I SandbergM M Souweidane
Sep 6, 2006·Neurosurgical Review·Hidetoshi KasuyaTomokatsu Hori
Oct 27, 2009·Brain Tumor Pathology·Satoshi NakasuKazuhiko Nozaki
Jun 26, 2003·Neurosurgery·Makoto NakamuraMadjid Samii
Aug 4, 2005·Journal of Neuro-oncology·Alfredo Quiñones-HinojosaMichael W McDermott
Jun 28, 2011·Neurologia Medico-chirurgica·Takatoshi FujimotoFumihiko Nishimura
Sep 10, 2020·Frontiers in Oncology·Gervásio Teles Cardoso de CarvalhoRenata Toscano Simões
Jun 13, 2000·Journal of Neuropathology and Experimental Neurology·K LamszusL Kluwe
Aug 26, 2014·Journal of Neurosurgery·Bon-Jour LinDueng-Yuan Hueng
Jan 17, 2019·Neuro-oncology·Raymond Y HuangUNKNOWN International Consortium on Meningiomas
Mar 6, 1999·Journal of Neurosurgery·S NakasuJ Handa
Apr 3, 2016·Neurosurgical Review·Hao LiJizong Zhao
Jan 29, 2019·Neurologia Medico-chirurgica·Satoshi NakasuKen-Ichi Matsumura
Jun 2, 2001·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·C H KimS J Oh
Aug 24, 1999·Archives of Pathology & Laboratory Medicine·C M Abramovich, R A Prayson
Aug 12, 2021·Cancer Management and Research·Haibo TengJianguo Xu

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