PMID: 8950562Oct 1, 1996Paper

Meningitis due to enterotoxigenic Bacteroides fragilis

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
P AucherJ L Fauchère

Abstract

An enterotoxigenic strain of Bacteroides fragilis was the sole organism isolated from the cerebrospinal fluid of a two-and-a-half-month neonate who had a medullary-colonic fistula as part of a complex congenital malformation, but no brain abscess. A rapid latex particle agglutination test for detection of bacterial antigen was positive for Haemophilus influenzae type b, suggesting that Bacteroides fragilis and Haemophilus influenzae type b might share some capsular antigens. In order to determine the role of the enterotoxin with respect to virulence of the strain, antibodies to a 20 kDa protein were sought in the patient's serum, but Western blot of the culture supernatant revealed only antibodies to a 45 kDa bacterial protein. The patient was successfully treated with metronidazole and imipenem.

References

Nov 1, 1992·The Pediatric Infectious Disease Journal·D A Law, S C Aronoff
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Dec 1, 1988·The Pediatric Infectious Disease Journal·S A Webber, P Tuohy
Jul 1, 1987·Reviews of Infectious Diseases·H M Feder
Dec 1, 1987·Journal of Clinical Microbiology·L L MyersR B Sack
Jun 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·N KatoK Ueno
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Jun 1, 1995·Journal of Clinical Microbiology·M D PerkinsL B Reller

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Citations

Oct 16, 2007·Clinical Microbiology Reviews·Hannah M Wexler
Apr 16, 2009·Clinical Microbiology Reviews·Cynthia L Sears

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