Abstract
Zygomycosis is an infection caused by opportunistic fungi of the Zygomycetes class, specifically those from the Mucorales and Entomophthorales orders. It is an uncommon disease, mainly restricted to immunocompromised patients. We report a case of a 73-year-old male patient with a history of fever (39 degrees C) lasting for 1 day, accompanied by shivering, trembling, and intense asthenia. The patient was admitted to the intensive care unit with complex partial seizures, and submitted to orotracheal intubation and mechanical ventilation under sedation with midazolam. The electroencephalogram showed evidence of non-convulsive status epilepticus. There is no fast specific laboratory test that permits confirmation of invasive fungal disease. Unless the physician suspects this condition, the disease may progress rapidly while the patient is treated with broad-spectrum antibiotics. Differential diagnosis between fungal and bacterial infection is often difficult. The clinical presentation is sometimes atypical, and etiological investigation is not always successful. In the present case, the histopathological examination of the biopsy obtained from the right temporal lobe indicated the presence of irregular, round, thick-walled fungi fo...Continue Reading
References
Oct 1, 1985·Critical Care Medicine·W A KnausJ E Zimmerman
Nov 24, 1999·Journal of Clinical Microbiology·K VoigtK O'donnell
Feb 7, 2001·Clinical Microbiology Reviews·J A RibesD J Baker
Jun 14, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D P KontoyiannisK V Rolston
Mar 7, 2001·Archives of Pathology & Laboratory Medicine·J L FraterG W Procop
Jun 19, 2001·Gene·K Voigt, J Wöstemeyer
Jan 30, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R M Prabhu, R Patel
Jan 11, 2005·Current Opinion in Infectious Diseases·Richard N GreenbergJulie A Ribes
Jul 16, 2005·Clinical Microbiology Reviews·Brad SpellbergAshraf Ibrahim
Aug 5, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maureen M RodenThomas J Walsh
Aug 10, 2005·Seminars in Respiratory and Critical Care Medicine·Alison G Freifeld, Peter C Iwen
Nov 8, 2005·Journal of Clinical Microbiology·Peter C IwenStefano R Tarantolo
Dec 8, 2005·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Jack Brown
Feb 4, 2006·Journal of Clinical Microbiology·Patrick SchwarzEric Dannaoui
Mar 29, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M ChayakulkeereeJ R Perfect
Jun 20, 2007·Mycoses·Amit DiwakarS N Gaur
Aug 21, 2007·Surgical Neurology·Philippe MetellusFrançois Grisoli
Feb 15, 2008·The Journal of Antimicrobial Chemotherapy·Thomas R Rogers
Apr 24, 2009·Journal of Clinical Microbiology·E AlvarezJ Guarro
Citations
Mar 5, 2013·Eukaryotic Cell·Lalitha GadeAnastasia P Litvintseva
Mar 1, 2012·Current Fungal Infection Reports·Jose Sifuentes-OsornioL Alfredo Ponce-de-León
Nov 15, 2011·Mycologia·María Teresa Gómez-MuñozFrancisco Ponce-Gordo