Menopausal bone changes and incident fractures in diabetic women: a cohort study.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
N KhalilJane A Cauley

Abstract

The purpose of this study was to evaluate the rate of bone loss and incident fractures in women with diabetes mellitus (DM) across menopause. During menopause, DM women experienced bone mineral density (BMD) loss that was faster at hip and slower at spine and had a higher risk of fractures, perhaps because of their earlier menopause. The increasing DM epidemic will contribute to higher fracture burden. Women with DM have a higher risk of fractures independent of age, body mass index (BMI), and BMD. Our objective is to evaluate if women with DM experience greater bone loss and more fractures across menopause. Two thousand one hundred seventy one women, aged 42 to 52 years at baseline (1996), enrolled in the Study of Women's Health Across the Nation (SWAN), a prospective study, with 8 years of annual follow up. One thousand three hundred forty six (62%) completed annual visit 7 (2004). Women with baseline fasting blood glucose level of ≥126 mg/dl and those being treated for diabetes were designated as DM. Annual assessment of menopausal stage, BMD, and urinary N-telopeptide (NTx) were carried out. Rate of change in BMD across menopause and annual self-report data for risk of incident fractures by DM status were determined. Despit...Continue Reading

References

Jan 29, 1976·The New England Journal of Medicine·M E LevinL V Avioli
Oct 1, 1992·Journal of Epidemiology and Community Health·K MidthjellG Lund-Larsen
Mar 1, 1992·American Journal of Epidemiology·M C NevittD M Black
Apr 1, 1992·Journal of Epidemiology and Community Health·D B CleghornB E Nordin
Jan 1, 1991·Journal of Clinical Epidemiology·S A KayeR B Wallace
Oct 1, 1987·The Journal of Clinical Endocrinology and Metabolism·L Nilas, C Christiansen
May 1, 1995·Scandinavian Journal of Clinical and Laboratory Investigation·U RishaugS Vaaler
Oct 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J VerhaegheR Bouillon
Dec 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P RavnC Christiansen
Aug 1, 1997·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·D HansP J Meunier
Jun 22, 1999·Menopause : the Journal of the North American Menopause Society·R López-LópezJ M Malacara
Jul 27, 2001·Diabetes·J S DormanUNKNOWN Familial Autoimmune and Diabetes (FAD) Study
Jan 15, 2003·Human Reproduction·J L LuborskyN Santoro
May 4, 2004·Journal of the American College of Cardiology·Paolo RaggiTracy Q Callister
Jun 5, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Elsa S StrotmeyerUNKNOWN Health ABC Study
Sep 10, 2004·The Journal of Clinical Endocrinology and Metabolism·Mishaela R Rubin, Shonni J Silverberg
Mar 15, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Ann V SchwartzUNKNOWN Health ABC Study
Jan 13, 2006·The Journal of Clinical Endocrinology and Metabolism·MaryFran R SowersBruce Ettinger
Jun 8, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A H HolmbergK Akesson
Jun 28, 2006·Diabetes Care·Mohsen JanghorbaniFrank Hu
Oct 28, 2006·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P Vestergaard
Dec 6, 2006·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Russel BurgeAnna Tosteson
Mar 30, 2007·Diabetes Care·Lorraine L LipscombeGillian A Hawker
Jun 19, 2007·American Journal of Epidemiology·Mohsen JanghorbaniFrank B Hu
Sep 29, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A Grey
Oct 11, 2007·Current Osteoporosis Reports·Ann V Schwartz, Deborah E Sellmeyer
Dec 28, 2007·The Journal of Clinical Endocrinology and Metabolism·Joel S FinkelsteinRobert M Neer
Jul 15, 2009·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Moira A PetitUNKNOWN Osteoporotic Fractures in Men (MrOs) Study Group
Jan 29, 2010·Diabetes Care·UNKNOWN American Diabetes Association

❮ Previous
Next ❯

Citations

Nov 11, 2011·The Journal of Clinical Endocrinology and Metabolism·Shinya IshiiArun S Karlamangla
Aug 7, 2012·The Journal of Clinical Endocrinology and Metabolism·Shinya IshiiArun S Karlamangla
Mar 29, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J Starup-LindeP Vestergaard
Feb 18, 2016·Current Diabetes Reports·Carrie A Karvonen-GutierrezCatherine Kim
Apr 27, 2013·Climacteric : the Journal of the International Menopause Society·A Monterrosa-CastroUNKNOWN Collaborative Group for Research of the Climacteric in Latin America (REDLINC)
Aug 13, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Y FanY Liu
Oct 4, 2011·Obstetrics and Gynecology Clinics of North America·Joan C LoJoel S Finkelstein
Jun 2, 2015·Bone·Ann V Schwartz
Nov 5, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Lora M GiangregorioJohn A Kanis
Aug 29, 2013·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Preethi SrikanthanArun S Karlamangla
Sep 15, 2015·The Lancet. Diabetes & Endocrinology·Vikram V ShanbhogueMary L Bouxsein
Oct 2, 2014·Journal of Bone and Mineral Metabolism·Hong Da ShaoGuang Yu Tang
Apr 14, 2016·Aging Clinical and Experimental Research·Joanna Dytfeld, Michał Michalak
Jan 27, 2015·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·T MontalciniC Gazzaruso
Oct 28, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·K RuppertD H Solomon
Jan 30, 2019·Diabetes Care·Guowei LiUNKNOWN CaMos Research Group
Aug 23, 2019·Menopause : the Journal of the North American Menopause Society·Lijuan YangXuejiang Gu
Jun 14, 2016·The Journal of Clinical Endocrinology and Metabolism·Po-Yin ChangJennifer S Lee
Nov 7, 2019·Menopause : the Journal of the North American Menopause Society·Lijuan YangXuejiang Gu
Sep 17, 2017·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·W D LeslieL M Lix
Jan 8, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E P ThongH J Teede

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
S VasikaranIOF-IFCC Bone Marker Standards Working Group
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
M F SowersStudy of Women's Health Across the Nation
© 2021 Meta ULC. All rights reserved