Menses Requires Energy: A Review of How Disordered Eating, Excessive Exercise, and High Stress Lead to Menstrual Irregularities

Clinical Therapeutics
Kimberly Huhmann

Abstract

Functional hypothalamic amenorrhea secondary to low weight, excessive exercise, and/or high levels of stress is common among young women. Adolescence is a time in development that a positive energy balance is crucial for puberty, menarche, and regular menstruation. Disordered eating and eating disorders are the third most common chronic illness and tend to start during puberty. High-level athletes, specifically young girls participating in ballet, running, gymnastics, and figure skating, are at risk of developing hypothalamic amenorrhea from excessive exercise and inability to meet the energy needs of the body. Dysfunction of the hypothalamic-pituitary-ovarian axis leads to a hypoestrogenic state. Low levels of estrogen have a negative effect on bone health, sexual maturation, sexual function, and fertility. Puberty has the highest rate of bone accrual in a female's life. Adequate nutrition, physical activity, and estrogen are crucial for bone development and prevention of osteoporosis. Recognition and early intervention are necessary to limit the irreversibility of some of these effects. A review of literature was completed to gather epidemiologic data, pathophysiology, diagnostic criteria, recommended laboratory/imaging, and ...Continue Reading

Citations

Aug 28, 2021·Reproductive Biomedicine Online·Gemma FabozziFilippo Maria Ubaldi
Sep 29, 2021·Journal of Women's Health·Noelle OzimekNicole C Woitowich

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