Menstrual and reproductive history and use of exogenous sex hormones and risk of thyroid cancer among women: a meta-analysis of prospective studies

Cancer Causes & Control : CCC
Saverio CainiSara Gandini

Abstract

Thyroid cancer has a higher incidence in women than in men, and it has been hypothesized that hormonal factors may explain such disparity. We performed a meta-analysis of observational prospective studies to investigate the association between menstrual and reproductive variables and exogenous hormone use and the risk of thyroid cancer among women. We calculated summary relative risks and 95% confidence intervals (95% CI) using random effect models. Overall, 5,434 thyroid cancer cases from twenty-four papers were included. Increasing age at first pregnancy/birth (SRR 1.56, 95% CI 1.01-2.42) and hysterectomy (SRR 1.43, 95% CI 1.15-1.78) were associated with thyroid cancer risk. Women that were in menopause at enrolment had a reduced thyroid cancer risk (SRR 0.79, 95% CI 0.62-1.01). No other menstrual, reproductive, and hormonal variable was associated with thyroid cancer risk. Menstrual and reproductive factors may play a role in the etiology of thyroid cancer, possibly through the mediation of estrogen receptors.

References

Apr 1, 1989·American Journal of Epidemiology·L A BrintonR Hoover
Jan 1, 1987·Epidemiologic Reviews·S Greenland
Sep 1, 1984·American Journal of Epidemiology·A M McTiernanJ R Daling
Jan 1, 1995·Cancer Causes & Control : CCC·M R GalantiB Pettersson
Jul 29, 1996·International Journal of Cancer. Journal International Du Cancer·I PerssonC Schairer
Jun 1, 1997·International Journal of Epidemiology·R LuotoM Hakama
Jun 10, 1998·American Journal of Epidemiology·B ModanB Lunenfeld
Sep 10, 1999·International Journal of Epidemiology·F FiorettiC La Vecchia
Feb 7, 2001·The Journal of Clinical Endocrinology and Metabolism·Y FleuryL Portmann
Feb 27, 2001·Statistics in Medicine·P MacaskillL Irwig
Mar 10, 2001·The Journal of Clinical Endocrinology and Metabolism·D ManoleM Derwahl
Jul 31, 2001·International Journal of Cancer. Journal International Du Cancer·C IribarrenG D Friedman
Feb 12, 2002·Statistics in Medicine·Hans C van HouwelingenTheo Stijnen
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Jan 28, 2003·American Journal of Obstetrics and Gynecology·Riitta LuotoEero Pukkala
Apr 9, 2005·International Journal of Cancer. Journal International Du Cancer·Stephanie A Navarro SilveraThomas E Rohan
May 20, 2005·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Rachel E NealeMats Talbäck
Sep 10, 2005·American Journal of Obstetrics and Gynecology·Michelle D AlthuisLouise A Brinton
Oct 13, 2005·International Archives of Occupational and Environmental Health·E Y WongH Checkoway
Nov 18, 2006·Cancer Causes & Control : CCC·Karin A RosenblattDavid B Thomas
Aug 16, 2008·Cancer Causes & Control : CCC·Karin A RosenblattDavid B Thomas
Nov 20, 2008·Cancer Causes & Control : CCC·Briseis A KilfoyYawei Zhang
Jan 27, 2009·International Journal of Cancer. Journal International Du Cancer·Tsogzolmaa DorjgochooWei Zheng
Mar 14, 2009·Journal of Women's Health·Truong-Minh PhamUNKNOWN Japan Collaborative Cohort Study Group
Dec 3, 2009·American Journal of Epidemiology·Cari L MeinholdAmy Berrington de González
May 15, 2010·Endocrine Journal·Min-Hee KimHo-Young Son
Oct 29, 2010·Revue D'épidémiologie Et De Santé Publique·C Leux, P Guénel
Nov 20, 2010·Human Reproduction·B KällénP Otterblad Olausson
Dec 15, 2010·Future Oncology·Reza RahbariElectron Kebebew
Feb 8, 2011·CA: a Cancer Journal for Clinicians·Ahmedin JemalDavid Forman
Jun 21, 2011·Journal of Thyroid Research·Ana Paula Santin, Tania Weber Furlanetto
Jul 28, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Pamela L Horn-RossLeslie Bernstein
Sep 7, 2011·British Medical Bulletin·Mark P J Vanderpump
Feb 22, 2012·Human Reproduction·A-N Yli-KuhaE Hemminki
May 10, 2012·The Journal of Clinical Endocrinology and Metabolism·Sanjeeve BalasubramaniamAlina V Brenner
Oct 24, 2012·Cancer Causes & Control : CCC·Geoffrey C KabatThomas E Rohan
Jan 17, 2013·The Journal of International Medical Research·Z G ZhaoH Y Cao
Jun 6, 2013·Journal of Cancer Epidemiology·Gabriella PellegritiRiccardo Vigneri
Nov 2, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Wararat SungwaleeSupannee Promthet

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Citations

Dec 31, 2015·Cancer Medicine·Jingjing ZhuLang Wu
Jul 16, 2016·Nature Reviews. Endocrinology·Cari M Kitahara, Julie A Sosa
Mar 11, 2017·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Ho-Sun LeeMihi Yang
Oct 27, 2018·Pathology Oncology Research : POR·Xiaolin YangWeijuan Li
Jun 8, 2017·Frontiers in Endocrinology·Mariacarla MoletiFrancesco Vermiglio
Nov 14, 2018·International Journal of Endocrinology·R LaurettaM Appetecchia
Feb 8, 2019·Oxidative Medicine and Cellular Longevity·Caroline C FariaRodrigo S Fortunato
Feb 3, 2021·International Journal of Cancer. Journal International Du Cancer·Thérèse TruongFlorent de Vathaire
Feb 24, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Louise F WilsonSusan J Jordan
May 5, 2021·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Jane R SchubartDavid Goldenberg
Aug 8, 2021·International Journal of Environmental Research and Public Health·Young Ju JinHyo Geun Choi
May 16, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·John A BaronStephen Safe

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