Menstrual characteristics and ultrasonographic uterine cavity measurements predict bleeding and pain in nulligravid women using intrauterine contraception

Human Reproduction
Janina KaislasuoSatu Suhonen


Is small uterine cavity size as assessed by ultrasonography associated with bleeding problems or pain in nulligravid women using intrauterine contraception, or do other factors affect these parameters? Among levonorgestrel intrauterine system (LNG-IUS) users, small uterine cavity size is not associated with worsened clinical outcome, but is beneficial as women with the smallest cavity measurements were frequently amenorrhoeic and painless at the end of the first year but among copper intrauterine device (IUD) users, no associations between uterine cavity dimensions and clinical outcome were found. Nulligravid and nulliparous women have smaller uterine dimensions than parous women. Previously, many studies have revealed increased discontinuation rates of IUD use as a result of bleeding, pain or expulsion in these women, while recent studies with current models of IUS/IUDs indicate similar continuation and satisfaction rates irrespective of parity. In a pilot study, 165 adult nulligravid women requesting their first IUD between 1 January 2011 and 31 July 2012 were given a free choice between two IUDs with equal frames measuring 32 × 32 mm-the LNG-IUS 52 mg or a copper-releasing IUD. The women were followed for 1 year. The LNG-IUS...Continue Reading

Associated Clinical Trials


Jan 1, 1992·American Journal of Public Health·J Johnson, A H Whitaker
Jun 1, 1984·Contraception·K H KurzA A Haspels
Dec 1, 1982·Clinical Endocrinology·C G NilssonT Luukkainen
Mar 31, 2000·BJOG : an International Journal of Obstetrics and Gynaecology·T BackmanM Koskenvuo
Feb 14, 2004·Ultrasound in Medicine & Biology·Antonio Gadelha Da CostaFernando Marum Mauad
Dec 1, 2007·Climacteric : the Journal of the International Menopause Society·N H BjarnasonC Christiansen
Dec 18, 2007·Contraception·Jeffrey T JensenAntonio C Costales
Jul 1, 2009·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B R BenacerrafB Bromley
Sep 30, 2010·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Thomas D ShippBeryl R Benacerraf
Mar 23, 2011·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Lena MarionsInger Øverlie
Sep 22, 2012·Obstetrics and Gynecology·UNKNOWN Committee on Adolescent Health Care Long-Acting Reversible Contraception Working Group, The American College of Obstetrician
Oct 10, 2013·Obstetrics and Gynecology·Micaela Oʼneil-CallahanGina Secura
Jul 9, 2014·Obstetrics and Gynecology·Janina KaislasuoSatu Suhonen
Jul 22, 2014·American Journal of Obstetrics and Gynecology·Justin T DiedrichJeffrey F Peipert
Sep 2, 2014·Current Medicinal Chemistry·Gerasimos SiasosDimitris Tousoulis
Sep 10, 2014·Obstetrics and Gynecology·Tessa MaddenJeffrey F Peipert
Oct 1, 2014·Pediatrics·UNKNOWN Committee on Adolescence

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Jan 13, 2016·Human Reproduction Update·Stella IacovidesFiona C Baker
Feb 13, 2018·Archives of Gynecology and Obstetrics·Seyma FadilogluS Dilbaz
Mar 15, 2019·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Luis BahamondesMary E Gaffield
Nov 8, 2019·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Anna M TeunissenFrans J M E Roumen
Feb 7, 2020·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·José Angel EspinosaJosé Luis Bartha
Jul 22, 2020·Current Opinion in Pediatrics·Alexandra J EdwardsSarah Pitts
Jul 9, 2020·Journal of Clinical Medicine·Magdalena ZgliczynskaKatarzyna Kosinska-Kaczynska
Oct 6, 2019·Journal of Pediatric and Adolescent Gynecology·Dan Apter
Feb 9, 2021·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Fatemeh Tabatabaei, Mahdiyeh Masoumzadeh

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