Menstrual cycle and its disorders in women with congenital heart disease

Congenital Heart Disease
Willem DrenthenPetronella G Pieper

Abstract

To investigate the age at menarche, the prevalence of menstrual cycle (interval) disorders, and determinants in women with congenital heart disease (CHD). Using two CHD registries, 1802 (82%) of the 2196 women with CHD contacted (aged 18-58 years) provided written informed consent. After exclusion of patients with genetic disorders known to be associated with menstrual cycle disorders, 1593 eligible patients remained. Interviews by telephone and reviews of medical records were conducted. Overall, the age at menarche was slightly increased in women with CHD (13.3 vs. 13.1 years in the general population), mainly attributable to an increased prevalence of primary amenorrhea (n = 147; 9.2%). Other menstrual cycle disorders were documented: secondary amenorrhea (n = 181, 11.4%), polymenorrhea (n = 103, 6.5%), oligomenorrhea (n = 90, 5.6%), and menorrhagia (n = 117, 6.5%). The occurrence of these disorders also depended on the presence of cyanotic heart disease, surgical status, the number of surgical interventions, and the severity of CHD. Menstrual cycle disturbances, in particular primary amenorrhea, were frequently observed in this population. Patients with complex (cyanotic) heart disease needing repeated surgical interventions...Continue Reading

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Citations

Nov 2, 2016·Research in Cardiovascular Medicine·Zahra KhajaliMajid Maleki
Mar 30, 2010·Journal of Pediatric and Adolescent Gynecology·Delese E LaCourSally E Perlman
Feb 16, 2010·The American Journal of Cardiology·Matthäus ViglHarald Kaemmerer
Oct 30, 2010·The American Journal of Cardiology·Matthäus ViglHarald Kaemmerer
Jun 23, 2009·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Philip MoonsWerner Budts
Jan 13, 2012·Acta Psychiatrica Scandinavica·M V Seeman
Jul 9, 2021·Cardiology in the Young·Zahra GhaemmaghamiMahmood Sheikhfathollahi

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