PMID: 375004Jan 31, 1979Paper

meoA is the structural gene for outer membrane protein c of Escherichia coli K12

Molecular & General Genetics : MGG
L van AlphenL Havekes

Abstract

The isolation and characterization of two mutants of Escherichia coli K12 with an altered outer membrane protein c is described. The first mutant, strain CE1151, was isolated as a bacteriophage Me1 resistant strain which contains normal levels of protein c. Mutant cells adsorbed the phage with a strongly decreased rate. Complexes of purified nonheat modified wild type protein c and wild type lipopolysaccharide inactivated phage Me1, indicating that these components are required for receptor activity for phage Me1. When wild type protein c was replaced by protein c of strain CE1151, the receptor-complex was far less active, showing that protein c of strain CE1151 is altered. The second mutant produces a protein c with a decreased electrophoretic mobility, designated as protein c. An altered apparent molecular weight was also observed for one or more fragments obtained after fragmentation of the mutant protein with cyanogen bromide, trypsin and chymotrypsin. Alteration of protein c was not accompanied by a detectable alteration in protein b or its fragments. Both mutations are located at minute 48 of the Escherichia coli K12 linkage map. The results strongly suggest that meoA is the structural gene for protein c.

References

Aug 1, 1977·Journal of Bacteriology·J F Lutkenhaus
Aug 8, 1977·Biochemical and Biophysical Research Communications·J SekizawaM Inouye
Dec 14, 1977·Molecular & General Genetics : MGG·P BavoilK von Meyenburg
Jan 31, 1979·Molecular & General Genetics : MGG·C VerhoefH Verheij
Mar 17, 1977·Biochimica Et Biophysica Acta·B LugtenbergR Peters
Mar 16, 1976·European Journal of Biochemistry·C J Schmitges, U Henning
Sep 23, 1976·Molecular & General Genetics : MGG·W van AlphenW Berendsen
Feb 1, 1975·Journal of Bacteriology·H G Boman, D A Monner
May 1, 1970·European Journal of Biochemistry·W DrögeO Westphal
Sep 1, 1963·Proceedings of the National Academy of Sciences of the United States of America·M J OSBORN

❮ Previous
Next ❯

Citations

Aug 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·S ForstM Inouye
Jan 31, 1979·Molecular & General Genetics : MGG·C VerhoefH Verheij
Dec 1, 1978·FEBS Letters·B LugtenbergW van Alphen
Jan 1, 1986·Critical Reviews in Microbiology·T Nakae
Jan 1, 1980·Molecular & General Genetics : MGG·A P PugsleyC A Schnaitman
Jan 1, 1980·Journal of Supramolecular Structure·M N HallT J Silhavy
Dec 1, 1989·Microbiological Reviews·J B StockA M Stock
Jan 1, 1983·Journal of Bacteriology·H NikaidoJ Foulds
Mar 26, 1980·Biochimica Et Biophysica Acta·P W Kühl
Mar 1, 1985·Microbiological Reviews·H Nikaido, M Vaara
Aug 1, 1994·Journal of Bacteriology·N RamaniM Freundlich
Mar 1, 1980·Microbiological Reviews·B J Bachmann, K B Low

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Related Papers

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Eva Maria Delmo WalterRoland Hetzer
Proceedings of the National Academy of Sciences of the United States of America
N LeeM Inouye
© 2021 Meta ULC. All rights reserved