Mepilex Lite dressings for the management of radiation-induced erythema: a systematic inpatient controlled clinical trial.

The British Journal of Radiology
K V DiggelmannP M Herst

Abstract

Erythema occurs in 80-90% of women treated for breast cancer with radiation therapy. There is currently no standard treatment for radiation-induced skin reactions. This study investigates the clinical efficacy of Mepilex Lite dressings in reducing radiation-induced erythema in women with breast cancer. A total of 28 patients were recruited; of these, 24 participants presented with 34 erythematous areas of skin for analysis. When erythema was visible, each affected skin area was randomly divided into two similar halves: one half was treated using Mepilex Lite dressings, the other half with standard aqueous cream. Skin reactions were assessed by the Radiation-Induced Skin Reaction Assessment Scale. We also evaluated any potential dose build-up by the dressings using a white water phantom, the dose distribution over the breast via thermoluminescent dosimeters (TLDs) and the surface skin temperature with an infrared thermographic scanner. Mepilex Lite dressings significantly reduced the severity of radiation-induced erythema compared with standard aqueous cream (p <0.001), did not affect surface skin temperature and caused only a small (0.5 mm) dose build-up. TLD measurements showed that the inframammary fold was exposed to signifi...Continue Reading

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Citations

Jul 16, 2013·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Nao TamaiHiromi Sanada
Aug 15, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rebecca K S WongMario E Lacouture
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Feb 4, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Patries M HerstMarieke L Jasperse
May 24, 2014·British Journal of Nursing : BJN·Ellen Trueman, Lesley Taylor
Mar 13, 2014·British Journal of Nursing : BJN·Deborah Glover, Victoria Harmer
Sep 10, 2014·British Journal of Nursing : BJN·Kàren Morgan
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Sep 29, 2015·International Journal of Palliative Nursing·Joyson Kodiyan, Kyle T Amber
Apr 19, 2017·European Journal of Cancer Care·M Fernández-CastroM E García-Puig
Jun 1, 2014·Journal of Medical Radiation Sciences·Patries M Herst

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