Mercapturic acid formation in the marmoset (Callithrix jacchus)

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
B E Hall, S P James

Abstract

Benzylmercapturic acid is a major metabolite of [methylene-14C]benzyl chloride in the marmoset, as in the rat. The excretion of the minor metabolites benzylmercapturic acid sulphoxide and benzylcysteine accounted for a greater proportion of the dose than in the rat. Excretion of hippuric acid as a metabolite of benzyl chloride was variable in the marmoset. Acetylation of S-benzyl- and S-pentyl-L-cysteine to the corresponding mercapturic acids was extensive in the marmoset. Trace amounts of the sulphoxides of these acids were also excreted.

References

Jan 15, 1977·The Biochemical Journal·G BrüsewitzW H Mennicke
May 1, 1978·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·R H Waring
Nov 1, 1978·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·C P DawesJ R Majer
Apr 1, 1973·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·S P James, D Needham
Oct 1, 1969·Biochemical Pharmacology·E A BarnsleyR H Waring
Mar 1, 1968·The Biochemical Journal·N M Sklan, E A Barnsley
Oct 1, 1968·The Biochemical Journal·S P JamesP B Wood
Jul 1, 1966·The Biochemical Journal·E A BarnsleyL Young
Sep 1, 1982·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·K GörlerH U Siehl
Sep 1, 1958·The Biochemical Journal·R H KNIGHT, L YOUNG
Apr 1, 1959·The Biochemical Journal·H G BRAYS P JAMES
Jul 15, 1964·Biochimica Et Biophysica Acta·E A BARNSLEY

❮ Previous
Next ❯

Citations

Apr 30, 2005·Journal of Medical Primatology·L Hernández-LópezP L Nayudu
Jun 13, 2015·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·Panayotis PanagopoulosGlyn B Steventon
Jan 13, 2015·American Journal of Primatology·P A GarberA Di Fiore
Jan 1, 1991·International Archives of Occupational and Environmental Health·L AringerC G Elinder

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
K GörlerH U Siehl
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
R H Waring
European Journal of Drug Metabolism and Pharmacokinetics
R H Waring
International Archives of Occupational and Environmental Health
A HolménB Högstedt
© 2021 Meta ULC. All rights reserved