journal cover

Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4

The Journal of Clinical Investigation

Sep 1, 1995

P PrigentF Hirsch

Abstract

Mercurials may induce immune manifestations in susceptible individuals. Mercuric chloride (HgCl2) induced autoimmunity in the Brown Norway (BN) strain but an immuno-suppression in the Lewis strain with, however, autoreactive anti-class II T cells present in both strains. In the present ...read more

Mentioned in this Paper

Ifng
T-Lymphocyte
Spleen
Il4
CD23 Antigen
Mercuric chloride
Rats, Inbred BN
Gene Expression
B-Lymphocytes
Visual Suppression
Paper Details
References
  • References30
  • Citations48
123
  • References30
  • Citations48
12345

Similar Papers Found In These Feeds

Fc Receptors

Fc receptors (fcrs) mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Discover the latest research on Fc Receptors here.

Follicular T Helper Cells

Follicular t helper cells are an important subset of helper t-cells which help to the formation of germinal centers and b-cells differentiation. Discover the latest research on follicular t helper cells here.

B cells: Gene Expression

B lymphocytes are white blood cells that play a role in the adaptive immune system by secreting antibodies. Here is the latest research on gene expression in B cells.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

© 2020 Meta ULC. All rights reserved

Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4

The Journal of Clinical Investigation

Sep 1, 1995

P PrigentF Hirsch

PMID: 7657819

DOI: 10.1172/jci118185

Abstract

Mercurials may induce immune manifestations in susceptible individuals. Mercuric chloride (HgCl2) induced autoimmunity in the Brown Norway (BN) strain but an immuno-suppression in the Lewis strain with, however, autoreactive anti-class II T cells present in both strains. In the present ...read more

Mentioned in this Paper

Ifng
T-Lymphocyte
Spleen
Il4
CD23 Antigen
Mercuric chloride
Rats, Inbred BN
Gene Expression
B-Lymphocytes
Visual Suppression

Similar Papers Found In These Feeds

Fc Receptors

Fc receptors (fcrs) mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Discover the latest research on Fc Receptors here.

Follicular T Helper Cells

Follicular t helper cells are an important subset of helper t-cells which help to the formation of germinal centers and b-cells differentiation. Discover the latest research on follicular t helper cells here.

Related Papers

European Journal of Immunology

Th1/Th2 cytokine gene expression after mercuric chloride in susceptible and resistant rat strains

European Journal of ImmunologyOctober 1, 1996
K M GillespieP W Mathieson
Paper Details
References
  • References30
  • Citations48
123
  • References30
  • Citations48
12345
/papers/mercuric-chloride-a-chemical-responsible-for-t/7657819