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Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4

The Journal of Clinical Investigation

Sep 1, 1995

Philippe PrigentFrançois Hirsch

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Abstract

Mercurials may induce immune manifestations in susceptible individuals. Mercuric chloride (HgCl2) induced autoimmunity in the Brown Norway (BN) strain but an immuno-suppression in the Lewis strain with, however, autoreactive anti-class II T cells present in both strains. In the present ...read more

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  • Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4

    The Journal of Clinical Investigation

    Sep 1, 1995

    Philippe PrigentFrançois Hirsch

    PMID: 7657819

    DOI: 10.1172/jci118185

    Abstract

    Mercurials may induce immune manifestations in susceptible individuals. Mercuric chloride (HgCl2) induced autoimmunity in the Brown Norway (BN) strain but an immuno-suppression in the Lewis strain with, however, autoreactive anti-class II T cells present in both strains. In the present ...read more

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    • Citations45
    • References30
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