PMID: 11926235Apr 3, 2002Paper

Mercury uptake and kinetics after ingestion of dental amalgam

Journal of Dental Research
E af GeijersstamJ Ekstrand

Abstract

The aim of the present study was to investigate the G-1 uptake of mercury (Hg) after intake of a single dose of amalgam-Hg, followed by pharmacokinetic analysis of the data. Eleven volunteers without amalgam fillings ingested 1.00 g amalgam powder. Hg in plasma vs. time was analyzed with a two-compartment model by means of mixed-effects modeling. A fraction of the absorption rate of Hg to the central compartment was inversely proportional to the plasma ferritin levels. The population mean half-life of the terminal phase of Hg in plasma was 37 days, with a considerable standard deviation in the population. The absorbed fraction of the administered dose was estimated to be about 0.04%. It is concluded that the G-1 uptake of Hg is of quantitative importance during dental treatment.

References

Jun 1, 1990·Acta Odontologica Scandinavica·M MolinS Skerfving
Aug 1, 1986·The American Journal of Clinical Nutrition·W S WatsonR Hume
Dec 1, 1994·Environmental Health Perspectives·M BerglundM Vahter
May 1, 1997·Toxicology and Applied Pharmacology·L BjörkmanJ Ekstrand
Jan 1, 1997·Annual Review of Nutrition·R A Goyer
Apr 16, 1998·Journal of Dental Research·G Sandborgh-EnglundJ Ekstrand
May 20, 1998·Scandinavian Journal of Clinical and Laboratory Investigation·G Sandborgh-EnglundC Valtersson
Jun 19, 1998·Toxicology and Applied Pharmacology·G Sandborgh-EnglundJ Ekstrand
Mar 4, 1999·Toxicology and Applied Pharmacology·F JonssonG Johanson
Apr 9, 1999·Computer Methods and Programs in Biomedicine·E N Jonsson, M O Karlsson

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Citations

May 10, 2003·The Science of the Total Environment·Jan S VamnesNils R Gjerdet
Dec 31, 2005·Archives of Environmental Health·Gunilla Sandborgh-EnglundJan Ekstrand
Oct 12, 2010·Photomedicine and Laser Surgery·Marcelo Tomás de OliveiraGustavo Otoboni Molina
Oct 6, 2005·Environmental Health : a Global Access Science Source·Marika BerglundMarie Vahter
Oct 13, 2007·Environmental Health : a Global Access Science Source·Lars BjörkmanMarie Vahter
Feb 12, 2009·International Journal of Health Geographics·Marco VincetiFrancesca Rivieri
Jul 27, 2005·Toxicological Reviews·Amy M BrownawellMeryl H Karol
Jul 9, 2008·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Daniel E Rusyniak, Kristine A Nanagas
Apr 12, 2005·Environmental Research·E BárányA Oskarsson
Dec 26, 2013·Toxicology and Applied Pharmacology·James P K Rooney
Jul 15, 2009·Biochimie·Emmanuel CurisSimone Bénazeth
Apr 26, 2003·Journal of Toxicology and Environmental Health. Part a·Gunilla Sandborgh-EnglundAnnika Loftenius
Jan 18, 2017·Acta Odontologica Scandinavica·Lars BjörkmanBirgitte F Lundekvam
Aug 7, 2014·The Journal of Contemporary Dental Practice·Marcelo Tomás OliveiraJefferson Ricardo Pereira

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