Merkel cell carcinoma: extended lymphadenectomy and reconstruction with biosynthetic prosthesis

Journal of Surgical Case Reports
Enrico Coppola BottazziFrancesco Crafa

Abstract

Merkel cell carcinomas (MCC) is an aggressive neuroendocrine carcinoma originating from the Merkel cell in the dermo-epidermal junction. Only 10% of MCC occur on the skin of the trunk. We report a case of Merkel's abdominal carcinomas treated with extensive inguinal lymphadenectomy and reconstruction of the abdominal wall and inguinal canal using prosthesis GORE® BIO-A®. Immunohistochemical analysis by tumor-specific markers is crucial for diagnosis and permits differentiation from other tumors of the skin. MCC is an aggressive tumor with poor prognosis. For primary tumors without indications of the presence of organ metastases complete surgical excision is the gold standard. Gore BIO-A is a biosynthetic prosthesis with manageable structure that allows it to be positioned and shaped according to needs, its strength provides for excellent support for the reconstruction of the inguinal canal wall.

References

Oct 25, 2003·Journal of the American Academy of Dermatology·Maria Agelli, Limin X Clegg
Jan 19, 2008·Science·Huichen FengPatrick S Moore
Apr 30, 2009·Experimental Dermatology·Roland HoubenJürgen C Becker
Jul 30, 2009·Journal of Cutaneous Pathology·Jorge Albores-SaavedraDonald Earl Henson
Mar 13, 2014·Journal of the National Comprehensive Cancer Network : JNCCN·Christopher K BichakjianUNKNOWN National comprehensive cancer network

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