PMID: 8599460Oct 1, 1995Paper

Merkel cell carcinoma with a desmoplastic portion

The American Journal of Dermatopathology
S KossardM Killingsworth

Abstract

Merkel cell carcinoma of the skin usually has a trabecular, intermediate-cell or small-cell pattern of differentiation. We report the case of a 66-year-old man who developed a progressive multinodular plaque that showed a prominent desmoplastic component on preliminary biopsy. Immunohistochemical and ultrastructural studies and the final surgical specimen confirmed that the tumor was a Merkel cell carcinoma. The presence of desmoplasia may mask the diagnosis of Merkel cell carcinoma.

Citations

Jul 11, 2009·The American Journal of Dermatopathology·Meghan Dubina, Gary Goldenberg
Jul 21, 2007·Journal of Cutaneous Pathology·Nigel J Ball, Grace Tanhuanco-Kho
Mar 7, 2001·Journal of Cutaneous Medicine and Surgery· Tai PTJ Gilchrist

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