Mesenchymal chondrosarcoma treated with total en bloc spondylectomy for 2 consecutive lumbar vertebrae resulted in continuous disease-free survival for more than 5 years: case report

Spine
Yoshiro MatsudaHaruyasu Yamamoto

Abstract

A case report of an extremely rare malignant spinal tumor successfully treated with total en bloc spondylectomy and chemotherapy. To describe points for consideration when an osteogenic lesion in the spine is diagnosed and treated. Primary mesenchymal chondrosarcoma in the spine is extremely rare. There were no reports of this tumor being treated with spondylectomy to achieve total surgical resection with a wide margin followed by chemotherapy. A 44-year-old female presented with low back pain and left flank pain. Magnetic resonance imaging and computerized tomography showed an osteosclerotic tumor of the lumbar vertebrae. Tc-99m HMDP bone scintigraphy was positive, but thallium-201 scintigraphy and gallium scintigraphy were negative. The patient was diagnosed as having chondrosarcoma based on biopsy findings. To resect the tumor completely, total en bloc spondylectomy for 2 consecutive lumbar vertebrae was performed. However, the postoperative pathologic diagnosis was extremely difficult because the patient was initially suspected to have osteosarcoma, but the final diagnosis was mesenchymal chondrosarcoma. Five years after surgery, there have not been any signs of local recurrence or distant metastasis, and the patient has re...Continue Reading

References

Sep 1, 1978·Spine·M B CaminsR C Marcove
Apr 1, 1976·Journal of Neurosurgery·R L Blaylock, L G Kempe
Jan 1, 1992·Journal of Cancer Research and Clinical Oncology·H TsuchiyaK Tomita
Feb 1, 1991·The Journal of Pathology·R Reid
Jan 1, 1990·Scandinavian Journal of Thoracic and Cardiovascular Surgery·L Dernevik, S Larsson
Sep 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A EliasK H Antman
Jan 1, 1989·Surgical Neurology·S T LeeM D Tsai
Feb 1, 1985·Journal of Surgical Oncology·Y HertzanuM Cohen
Oct 1, 1970·American Journal of Surgery·M ArlenR C Marcove
Jan 1, 1980·Cancer·D J PritchardB E Medley
Oct 1, 1994·International Orthopaedics·K TomitaY Toribatake
Feb 15, 1993·International Journal of Radiation Oncology, Biology, Physics·J P AustinJ E Munzenrider
Mar 1, 1997·The Journal of Bone and Joint Surgery. American Volume·N KawaharaG Kinoshita
Aug 25, 1997·European Radiology·N YüntenR N Sener
Mar 27, 2004·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Kenshi SakayamaHaruyasu Yamamoto

❮ Previous
Next ❯

Citations

Feb 19, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Pongsthorn ChanplakornWichien Laohacharoensombat
Aug 7, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Lin HuangHui-Yong Shen
Sep 24, 2009·Journal of Neurosurgery. Pediatrics·Paul KlimoLiliana C Goumnerova
Dec 25, 2007·Neurosurgery Clinics of North America·Gregory S McLoughlinJean-Paul Wolinsky
Mar 26, 2011·Sarcoma·Pavlos KatonisApostolos Karantanas
Jun 2, 2011·Case Reports in Medicine·Kalliopi AlpantakiPavlos Katonis
Aug 4, 2010·Pediatric Hematology and Oncology·Serhan KüpeliMünevver Büyükpamukçu
Dec 20, 2017·Spine Surgery and Related Research·Katsuhito YoshiokaHiroyuki Tsuchiya
Mar 20, 2021·The Indian Journal of Radiology & Imaging·Ahmed SaadRajesh Botchu
Nov 30, 2021·The Journal of International Medical Research·Chih-Hisu TuCheng-Di Chiu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved