Mesenchymal cystic hamartoma of the lung

The New England Journal of Medicine
E J Mark

Abstract

Mesenchymal hamartomatous nodules and cysts in the lungs caused hemoptysis, pneumothorax, hemothorax, pleuritic chest pain, dyspnea of slight or moderate degree, or a combination of these signs and symptoms in five patients. In four cases the disease was multifocal and bilateral. The nodules were composed of primitive mesenchymal cells subdivided into papillae by a plexus of small airways lined with respiratory epithelium. The nodules grew slowly in number and size over the years and apparently became cystic when they reached a diameter of about 1 cm. The cysts had a cambium layer of mesenchymal cells and were lined with normal or metaplastic respiratory epithelium. In general, the disease had an indolent course. The most serious complications were sudden hemorrhage into a cyst from large systemic arteries supplying the walls of the cysts, pneumothorax or hemothorax from rupture of a subpleural cyst, and malignant transformation in one case. This disease appears to represent a distinct clinicopathological entity, which I term mesenchymal cystic hamartoma of the lung.

References

Jul 1, 1979·AJR. American Journal of Roentgenology·T E SumnerL D Shaffner
Jan 1, 1979·Scandinavian Journal of Thoracic and Cardiovascular Surgery·J L SvennevigN P Boye
Sep 1, 1980·AJR. American Journal of Roentgenology·J D GodwinP C Goodman
Apr 1, 1980·Pediatric Radiology·A G WeinbergT P Votteler
Jun 1, 1963·Thorax·C STEPHANOPOULOS, H CATSARAS

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Citations

Mar 25, 2011·Surgery Today·Mehmet Oğuzhan OzyurtkanAkin Eraslan Balci
Mar 13, 2009·General Thoracic and Cardiovascular Surgery·Masayuki ChidaHajime Odajima
Jan 11, 2012·General Thoracic and Cardiovascular Surgery·Akira MogiHiroyuki Kuwano
Nov 1, 1988·Cancer Genetics and Cytogenetics·P Dal CinA A Sandberg
Jun 6, 2000·The Journal of Pediatrics·J C PicaudG Bellon
Aug 7, 2003·Journal of Pediatric Hematology/oncology·Yasir IqbalSaud Al-Jaddan
Feb 27, 2009·Journal of Thoracic Imaging·Frederico F Souza, Eleanor Chen
Dec 1, 1992·Thorax·M MushtaqJ S Mann
Feb 1, 1990·Mayo Clinic Proceedings·M G JosephE A Gaensler
May 29, 2012·The Annals of Thoracic Surgery·Hong ZhuXiaoge Zhou
Sep 1, 1993·Journal of Pediatric Surgery·B J HancockP P Collin
Feb 18, 2003·Respiratory Medicine·V CottinJ F Cordier
Aug 31, 2013·Thorax·Erik H F M van der HeijdenMonica Looijen-Salamon
Jul 1, 1988·Chest·J D TruwitE L Dyer
Aug 16, 2016·The Korean Journal of Thoracic and Cardiovascular Surgery·Young Uk LeeJong Hyun Baek
Dec 21, 2000·Pathology International·Y TakeshimaK Inai
Dec 9, 2010·Rare Tumors·Massimiliano PaciGiorgio Sgarbi
Apr 15, 1990·Cancer·T TraweekN Azumi
Jan 1, 1989·Pediatric Pathology·K E Bove
May 9, 2019·The New England Journal of Medicine·Maria Apellaniz-RuizWilliam D Foulkes
May 4, 2020·General Thoracic and Cardiovascular Surgery·M LeopizziA Pernazza
Jul 9, 2008·Archives of Pathology & Laboratory Medicine·Megan K Dishop, Supriya Kuruvilla
Feb 24, 2001·The American Journal of the Medical Sciences·J Kelly, J Moss

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