Mesenchymal stem cell therapy in cats: Current knowledge and future potential

Journal of Feline Medicine and Surgery
Jessica M Quimby, Dori L Borjesson

Abstract

Practical relevance: Stem cell therapy is an innovative field of scientific investigation with tremendous potential for clinical application in veterinary medicine. Based on the known desirable immunomodulatory properties of mesenchymal stem cells, this therapy holds promise for the treatment of a variety of inflammatory diseases in cats. This review details our current understanding of feline stem cell biology and proposed mechanism of action. Studies performed in feline clinical trials for diseases including gingivostomatitis, chronic enteropathy, asthma and kidney disease are summarized, with the goal of providing an overview of the current status of this treatment modality and its potential for the future.

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Citations

Jun 7, 2019·World Journal of Stem Cells·Akari SasakiIchiro Sekiya
Oct 12, 2018·Stem Cells Translational Medicine·Julia MarchequeLaura Perin
Oct 24, 2019·BMC Veterinary Research·Inês Esteves DiasPedro Pires Carvalho
Jan 28, 2021·Animals : an Open Access Journal From MDPI·Antonio J VillatoroJosé Becerra
Mar 23, 2021·Frontiers in Veterinary Science·Julie BenningtonJ Koudy Williams
Apr 20, 2021·Frontiers in Cell and Developmental Biology·Rebecca M HarmanGerlinde R Van de Walle
Jun 23, 2021·Tissue Engineering. Part C, Methods·Zhuoming LiuLaxminarayana R Devireddy

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