Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Neurodegenerative Diseases.

European Neurology
Panpan YaoQin Yu

Abstract

Neurodegenerative disease is a kind of chronic, progressive nervous system disease characterized by neuron degeneration or apoptosis. Current treatments cannot prevent the development of the disease. Possible alternative treatments include cell therapy, especially with the use of mesenchymal stem cells (MSCs). MSCs are pluripotent stem cells with capacities for self-renewal and multidirectional differentiation. MSCs may serve as a reliable source of neural cells for potential cell replacement therapy or regenerative medicine treatment. Here, we summarized the therapeutic mechanisms of MSCs and how they can contribute to the development of treatments for neurodegenerative diseases.

Citations

Jan 15, 2021·International Journal of Molecular Sciences·Ka Young Kim, Keun-A Chang
Mar 3, 2021·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Milad Ahani-NahayatiAli Hassanzadeh
Nov 5, 2021·European Journal of Histochemistry : EJH·Marina BoidoAlessandro Vercelli

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