Mesh-augmented versus direct abdominal closure in patients undergoing open abdomen treatment

Hernia : the Journal of Hernias and Abdominal Wall Surgery
Manuel O JakobGuido Beldi

Abstract

Open abdomen (OA) may be required in patients with abdominal trauma, sepsis or compartment syndrome. Vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM) is a widely used approach for temporary abdominal closure to close the abdominal wall. However, this method is associated with a high incidence of re-operations in short term and late sequelae such as incisional hernia. The current study aims to compare the results of surgical strategies of OA with versus without permanent mesh augmentation. Patients with OA treatment undergoing vacuum-assisted wound closure and an intraperitoneal onlay mesh (VAC-IPOM) implantation were compared to VAWCM with direct fascial closure which represents the current standard of care. Outcomes of patients from two tertiary referral centers that performed the different strategies for abdominal closure after OA treatment were compared in univariate and multivariate regression analysis. A total of 139 patients were included in the study. Of these, 50 (36.0%) patients underwent VAC-IPOM and 89 (64.0%) patients VAWCM. VAC-IPOM was associated with reduced re-operations (adjusted incidence risk ratio 0.48 per 10-person days; CI 95% = 0.39-0.58, p < 0.001), reduced duration of stay on int...Continue Reading

References

Jun 7, 2007·Hernia : the Journal of Hernias and Abdominal Wall Surgery·M van't RietJ Jeekel
Apr 1, 2008·Annals of Surgery·Patrick T ConnollyGordon L Carlson
May 26, 2011·The Journal of Trauma·Nirav Y PatelMichelle A Mathiason
Aug 19, 2011·World Journal of Surgery·Froukje J VerdamJos P A M Vroemen
Mar 10, 2012·World Journal of Surgery·Moritz ScholtesGuido Beldi
Mar 5, 2013·Hernia : the Journal of Hernias and Abdominal Wall Surgery·A BrandlR Kafka-Ritsch
Sep 21, 2013·Journal of the American College of Surgeons·Alfredo M CarbonellMichael J Rosen
Nov 26, 2013·The British Journal of Surgery·D G WeberZ J Balogh
Jun 12, 2014·Hernia : the Journal of Hernias and Abdominal Wall Surgery·P PeterssonU Petersson
Jan 18, 2017·Hernia : the Journal of Hernias and Abdominal Wall Surgery·A WillmsU Dietz
Feb 13, 2018·World Journal of Emergency Surgery : WJES·Federico CoccoliniFausto Catena

❮ Previous
Next ❯

Citations

Feb 6, 2020·Hernia : the Journal of Hernias and Abdominal Wall Surgery·N Poortmans, F Berrevoet
Oct 20, 2020·The Journal of Trauma and Acute Care Surgery·Manuel O Jakob, Guido Beldi
Oct 17, 2020·The Journal of Trauma and Acute Care Surgery·Manuel O JakobGuido Beldi
Nov 19, 2020·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Kurt Nirishan BoolakyTimothy Craig Hardcastle

❮ Previous
Next ❯

Software Mentioned

SPSS
IPOM
SPSS Statistics
VAC
VAWCM

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved