meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups

Chemical Communications : Chem Comm
Naama RubinsteinRoy Weinstain

Abstract

Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.

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Nov 17, 2015·Accounts of Chemical Research·Tomáš ŠolomekPetr Klán
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