Mesoporous silica nanoparticles in tissue engineering--a perspective

Nanomedicine
Jessica M RosenholmCecilia Sahlgren

Abstract

In this review, we summarize the latest developments and give a perspective on future applications of mesoporous silica nanoparticles (MSNs) in regenerative medicine. MSNs constitute a flexible platform for controlled delivery of drugs and imaging agents in tissue engineering and stem cell therapy. We highlight the recent advances in applying MSNs for controlled drug delivery and stem cell tracking. We touch upon novel functions of MSNs in real time imaging of drug release and biological function, and as tools to control the chemical and mechanical environment of stem cells. We discuss the need for novel model systems for studying biofunctionality and biocompatibility of MSNs, and how the interdisciplinary activities within the field will advance biotechnology research.

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Citations

Dec 10, 2016·Biomaterials Science·Jingchao LiGuoping Chen
Mar 23, 2017·Angewandte Chemie·Bernhard BaumannJürgen Groll
May 12, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Wenzhang ChaJinbo Li
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Aug 22, 2017·Therapeutic Delivery·Maren Preis, Jessica M Rosenholm
Apr 23, 2020·Advanced Materials·Ranjith Kumar KankalaKevin C-W Wu
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Apr 12, 2020·International Journal of Molecular Sciences·Chia-Hui LinChia-Hung Lee
Nov 10, 2020·IScience·Ranjith Kumar KankalaAi-Zheng Chen
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Nov 7, 2018·Biomaterials·Arnold LeidnerChristof M Niemeyer
Aug 11, 2021·Pharmaceutics·Elham RastegariYueh Chien

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Methods Mentioned

BETA
imaging technology
biosensing
chips

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