META: an MRI-based scoring system differentiating metastatic from osteoporotic vertebral fractures

The Spine Journal : Official Journal of the North American Spine Society
So KatoTaiji Kondo

Abstract

Magnetic resonance imaging (MRI) is useful for the differential diagnosis of osteoporotic vertebral fractures (OVFs) and metastatic vertebral fractures (MVFs), but no single finding is absolutely conclusive. The purpose of the present study was to create a scoring system to facilitate the correct diagnosis of MVFs by integrating several MRI findings. This is a retrospective and single-center observational study that attempts to create a diagnostic scoring system by discriminant analysis. We included 100 OVFs and 100 MVFs in thoracolumbar vertebrae of which MR images were obtained within 60 days from the suspected time of fractures. The sensitivity and specificity of known important MRI findings were assessed, and the classification accuracy of the scoring system was investigated. Seven MRI findings of these fractures were analyzed to evaluate their sensitivity and specificity. Using these findings as variables, discriminant analysis was performed in 140 fractures as a training set, and the classification accuracy was calculated in the remaining 60 fractures as a test set. Additionally, the images of these 60 fractures were reviewed by another blinded reviewer to investigate the interobserver reliability of each finding. All fin...Continue Reading

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Citations

Jan 23, 2016·Zeitschrift für Gerontologie und Geriatrie·Roland BiberH J Bail
Jul 12, 2018·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Julio UrrutiaSebastian Mobarec
Mar 7, 2020·Journal of the National Comprehensive Cancer Network : JNCCN·Estanislao AranaUNKNOWN Spanish Back Pain Research Network Task Force for the Improvement of Inter-Disciplinary Management of Spinal Metastasis

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