Meta-Analysis of Association Between Interleukin-1β C-511T Polymorphism and Chronic Periodontitis Susceptibility

Journal of Periodontology
Xian-Tao ZengMin Mao

Abstract

Many studies have been conducted to explore the association between interleukin (IL)-1β C-511T polymorphism and risk of chronic periodontitis (CP) but with different or even contradictory results. A meta-analysis was performed to further explore their association. PubMed, Chinese National Knowledge Infrastructure, and EMBASE were searched up to September 30, 2014 for relevant case-control studies. Two authors (D-YL and L-YX) independently selected studies and extracted data from included studies. The meta-analysis was performed using comprehensive meta-analysis software. Nineteen case-control studies involving 2,173 patients with CP and 3,900 healthy controls were included. Using a random-effects meta-analysis model, a non-significant association between IL-1β C-511T polymorphism and CP was identified (T versus C: odds ratio [OR] = 1.03, 95% confidence interval [CI] = 0.85 to 1.25; TT versus CC: OR = 1.03, 95% CI = 0.72 to 1.46; CT versus CC: OR = 0.96, 95% CI = 0.71 to 1.30; CT + TT versus CC: OR = 1.00, 95% CI = 0.74 to 1.34; TT versus CT + CC: OR = 1.05, 95% CI = 0.81 to 1.38), and sensitivity analysis indicated that the results were robust. Subgroup analyses also revealed a non-significant association. No publication bias w...Continue Reading

References

Sep 1, 1992·Human Molecular Genetics·F S di GiovineG W Duff
Jan 1, 1997·Journal of Clinical Periodontology·K S KornmanG W Duff
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Jan 1, 1997·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·S E BarbourJ G Tew
Aug 26, 1998·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·H Okada, S Murakami
Sep 2, 1998·Annals of Periodontology·K S Kornman, F S di Giovine
Oct 31, 1998·Journal of Clinical Periodontology·E A GoreG M Galbraith
Jul 10, 2002·Periodontology 2000·Jasim M Albandar, Thomas E Rams
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Oct 29, 2002·Cytokine & Growth Factor Reviews·Steve BirdChris J Secombes
Apr 27, 2004·Periodontology 2000·Erica Gemmell, Gregory J Seymour
Nov 22, 2005·Lancet·Bruce L PihlstromNewell W Johnson
Nov 24, 2005·Journal of Dental Research·P M BrettM Tonetti
Jun 21, 2006·Psychological Methods·Tania B Huedo-MedinaJuan Botella
Apr 25, 2007·Journal of Dental Research·L NibaliG S Griffiths
Aug 5, 2008·Journal of Clinical Periodontology·Georgios K NikolopoulosPantelis G Bagos
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Oct 2, 2009·Journal of Periodontology·Néstor J LópezLilian Jara
Oct 12, 2010·Archives of Oral Biology·Paula C TrevilattoSergio R P Line
Dec 29, 2010·Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research·R VijayalakshmiPamela Emmadi
Nov 8, 2011·Diabetologia·P M PreshawR Taylor
Jul 17, 2012·Cytokine·Ana Paula Ribeiro BraosiPaula Cristina Trevilatto
Apr 12, 2013·Periodontology 2000·Robert J Genco, Wenche S Borgnakke
Apr 18, 2013·The International Journal of Biological Markers·Liang HaoElizabeth L Y Ng
Jul 5, 2013·Bratislavské lekárske listy·A Atanasovska-StojanovskaM Spiroski
Oct 17, 2013·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Zhi-Gang LiWei-Wei Wu
Jan 28, 2014·DNA and Cell Biology·Keiko TanakaMasashi Arakawa
Sep 26, 2014·Acta Odontologica Scandinavica·Ramesh AmirisettyAnjana Munshi

❮ Previous
Next ❯

Citations

Oct 10, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Xiao-Lan RuanXu-Bin Ao
Jun 25, 2015·Journal of Evidence-based Medicine·Sheng LiXian-Tao Zeng
Jun 14, 2016·Journal of Periodontology·Xian-Tao ZengJoey S W Kwong
Sep 16, 2016·Contemporary Clinical Dentistry·Magali Silveira Monteiro RibeiroJacyara Maria Brito Macedo
Dec 10, 2016·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Zuzanna ŚlebiodaBarbara Dorocka-Bobkowska
Aug 2, 2017·Periodontology 2000·Jeffrey L EbersoleOctavio A Gonzalez
Jul 8, 2020·International Journal of Molecular Sciences·Petra Borilova LinhartovaLydie Izakovicova Holla
Jul 22, 2019·Archivum Immunologiae Et Therapiae Experimentalis·Aniela BrodzikowskaJan Kowalski
Aug 8, 2018·Frontiers in Physiology·Wen-Zhong XieUNKNOWN BPSC investigators
Feb 23, 2020·BMC Oral Health·Felipe Rodolfo Pereira da SilvaJosé Fernando Marques Barcellos
May 23, 2017·International Journal of Dentistry·Maélson Klever da SilvaDaniel Fernando Pereira Vasconcelos
Jan 5, 2020·International Journal of Oral Science·Ran ChengTao Hu
Feb 14, 2019·BMC Oral Health·Zahra HeidariHamidreza Mahmoudzadeh-Sagheb
Nov 24, 2020·Periodontology 2000·Luciana Macchion ShaddoxLuigi Nibali
Dec 18, 2020·Journal of Clinical Medicine·Małgorzata KozakAndrzej Pawlik

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.