Meta-analysis of clinical trials examining the benefit of structured home exercise in patients with peripheral artery disease

The British Journal of Surgery
J GolledgeDylan R Morris

Abstract

Supervised exercise is recommended for the management of peripheral artery disease (PAD); however, the uptake is limited. Structured home exercise programmes may be more feasible, but their effectiveness is unclear. This systematic review and meta-analysis examined the benefit of structured home exercise programmes for treating PAD in comparison to controls not receiving an exercise programme. A literature search was conducted to identify RCTs comparing structured home exercise with controls not receiving an exercise programme among patients with PAD. To be included, studies had to report outcomes from treadmill or corridor walking tests, or objective assessment of physical activity. Inverse variance-weighted meta-analysis was performed to compare changes in maximum walking distance and intermittent claudication onset distance in treadmill tests, walking distance during a 6-min walking test, and physical activity measured using a pedometer or accelerometer. Summarized results are presented in terms of standard deviation differences. Eleven randomized trials involving 807 patients were included. Follow-up ranged from 2 to 24 months; only one trial included follow-up beyond 12 months. Meta-analyses showed that structured home exe...Continue Reading

Associated Clinical Trials

Feb 11, 2021·Ivone Silva, Ivone Silva

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Citations

Oct 3, 2019·Current Opinion in Lipidology·Jonathan GolledgeGerald F Watts
Apr 21, 2020·Acta Physiologica·Philipp HillmeisterIvo Buschmann
Oct 24, 2019·BioMed Research International·Anna SpannbauerMaria T Szewczyk
May 19, 2020·European Journal of Preventive Cardiology·Rod S Taylor, Sally Singh
Feb 22, 2021·European Journal of Preventive Cardiology·Rod S Taylor, Sally Singh
Sep 30, 2020·Medicine and Science in Sports and Exercise·Andrew W GardnerJohn D Sorkin
Mar 23, 2021·Journal of Atherosclerosis and Thrombosis·Jonathan Golledge, Aaron Drovandi
Apr 10, 2020·Annals of Physical and Rehabilitation Medicine·Béatrice VillemurDominic Pérennou
Apr 28, 2020·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Jonathan GolledgeNicola W Burton
Apr 24, 2021·Journal of the American Heart Association·Shivshankar ThanigaimaniJonathan Golledge
May 4, 2020·La Revue de médecine interne·C Le HelloC Boissier
Jan 9, 2022·Nature Reviews. Cardiology·Jonathan Golledge

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