Meta-analysis of intravoxel incoherent motion magnetic resonance imaging in differentiating focal lesions of the liver

Medicine
Hongzhen WuWenjie Tang

Abstract

Accurate detection and characterization of focal liver lesions, including differentiation between malignant and benign lesions, are particularly important. The objective of this meta-analysis was to evaluate the parameters of intravoxel incoherent motion (IVIM), including apparent diffusion coefficient (ADC), pure molecular diffusion coefficient (D), perfusion-related diffusion coefficient (D*), and perfusion fraction (f) in differentiating focal liver lesions. IVIM method employed for focal liver lesion and the quality assessment of diagnostic studies were evaluated. Standardized mean differences and 95% confidence intervals were calculated. The heterogeneity was quantified with the I statistic. The difference between groups was analyzed according to the I values from 6 different studies using fixed effects or random effects models. Significant differences in ADC (P < .001) and D (P < .001) were observed between benign and malignant lesions. Moreover, significant differences in ADC (P < .001), D (P < .001), and f (P = .01) were found between hemangioma and hepatocellular carcinoma (HCC). In addition, no significant difference was observed between the metastases and HCC. D and ADC values were useful for the differentiation betw...Continue Reading

References

Sep 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D Le Bihan, R Turner
Nov 1, 1990·Radiology·R TurnerJ Pekar
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Mar 8, 2006·BMC Medical Research Methodology·Penny F WhitingJos Kleijnen
May 25, 2011·AJR. American Journal of Roentgenology·Dow-Mu KohMatthew R Orton
Oct 15, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ashkan A MalayeriKatarzyna J Macura
Oct 19, 2011·Annals of Internal Medicine·Penny F WhitingUNKNOWN QUADAS-2 Group
Nov 23, 2012·Journal of Magnetic Resonance Imaging : JMRI·Shintaro IchikawaTsutomu Araki
Jun 3, 2014·BMC Public Health·Victoria Abril-UlloaVictoria Arija
Dec 5, 2014·World Journal of Gastroenterology : WJG·Ji-Hua Shi, Pål-Dag Line
Sep 24, 2015·European Journal of Radiology Open·Yong CuiBachir Taouli
Jan 30, 2016·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Natsuhiko ShirotaKoichi Tokuuye
Oct 7, 2016·Acta Informatica Medica : AIM : Journal of the Society for Medical Informatics of Bosnia & Herzegovina : časopis Društva Za Medicinsku Informatiku BiH·Elma JahicAzra Husic Selimovic

❮ Previous
Next ❯

Citations

Mar 17, 2020·Journal of Medical Imaging and Radiation Oncology·Kevin My LoHui Jun Xu
Apr 17, 2020·Current Oncology Reports·Arya Haj-MirzaianAtif Zaheer
Sep 3, 2020·World Journal of Clinical Cases·Yun-Yun TaoXiao-Ming Zhang
May 15, 2021·The British Journal of Radiology·Roberto CannellaMarco Dioguardi Burgio
Jul 3, 2021·Journal of Clinical Medicine·Liberatore TramontanoValentina Brancato

❮ Previous
Next ❯

Software Mentioned

Review Manager
RevMan
IVIM
QUADAS

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Adrenocortical Carcinoma

Hepatocellular carcinoma is the most common type of primary liver cancer and frequently occurs in individuals with chronic liver diseases like cirrhosis. Here is the latest research.