Meta-analysis of prepectoral implant-based breast reconstruction: guide to patient selection and current outcomes.

Breast Cancer Research and Treatment
Olivia AbbateEric C Liao

Abstract

 This meta-analysis provides a large-scale comparison of prepectoral vs. subpectoral implant-based breast reconstruction, with primary outcomes of patient safety and efficacy. Literature review was performed via PRISMA criteria, 33 studies met inclusion criteria for prepectoral review and 13 studies met inclusion criteria for meta-analysis. Patient characteristics and per-breast complications were collected. Data were analyzed using Cochrane RevMan and IBM SPSS. In 4692 breasts of 3014 patients that underwent prepectoral breast reconstruction, rippling was observed as the most common complication, followed by seroma and skin flap necrosis. Meta-analysis demonstrated statistically significant decrease in odds of skin flap necrosis and capsular contracture in prepectoral groups compared to subpectoral groups. Odds of infection, seroma, and hematoma were equal between the two groups. Prepectoral breast reconstruction has surged in popularity in recent years. This review and large-scale analysis corroborates current literature reporting a favorable safety profile with emphasis on patient selection. Variability in skin flap thickness and vascularity mandates thoughtful selection of patients whose overall health and intra-operative s...Continue Reading

References

Jan 1, 1987·Aesthetic Plastic Surgery·W Holzgreve, F K Beller
Aug 28, 2007·Annals of Plastic Surgery·Karl H Breuing, Amy S Colwell
Feb 4, 2010·Plastic and Reconstructive Surgery·Yoon S ChunElof Eriksson
Sep 23, 2011·Aesthetic Surgery Journal·Maurice Y Nahabedian, Scott L Spear
Nov 1, 2012·Plastic and Reconstructive Surgery·Maurice Y Nahabedian
Dec 29, 2012·Plastic and Reconstructive Surgery·Claudia R AlbornozEvan Matros
Jun 15, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Marweh SchmitzRaymund E Horch
Oct 10, 2013·Plastic and Reconstructive Surgery·Scott L SpearTroy Pittman
May 29, 2015·Plastic and Reconstructive Surgery·Dennis C HammondElizabeth A O'Connor
Jul 17, 2015·Plastic and Reconstructive Surgery. Global Open·Hilton BeckerElizabeth G Hopkins
Feb 29, 2016·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Lin ZhuMichel Saint-Cyr
Sep 1, 2016·Plastic and Reconstructive Surgery. Global Open·Edward M KobraeiEric C Liao
Dec 16, 2016·Plastic and Reconstructive Surgery. Global Open·Robert H SchnarrsKerri A Rossmeier
Dec 16, 2016·Plastic and Reconstructive Surgery. Global Open·Ara A SalibianNolan S Karp
Jan 26, 2017·Plastic and Reconstructive Surgery·Steven SigaloveAllen Gabriel
May 22, 2017·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M-K TasoulisR Vidya
Jun 16, 2017·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Sandhya PandeyDinesh Kumar Sivakumar
Aug 24, 2017·Plastic and Reconstructive Surgery. Global Open·Lynne N BettingerDaniel I Jacobs
Oct 25, 2017·Plastic and Reconstructive Surgery·Ryan P Ter Louw, Maurice Y Nahabedian
Nov 23, 2017·Plastic and Reconstructive Surgery·Maurice Y Nahabedian, Costanza Cocilovo
Nov 23, 2017·Plastic and Reconstructive Surgery·Glyn JonesEric Elwood
Apr 11, 2018·Plastic and Reconstructive Surgery. Global Open·Steven SigaloveAllen Gabriel
Jul 7, 2018·Annals of Surgical Oncology·Catherine J SinnottAnke Ott Young
Jul 13, 2018·Gland Surgery·Eleni Tousimis, Michelle Haslinger
Sep 27, 2018·Plastic and Reconstructive Surgery·Maurice Y Nahabedian
Oct 3, 2018·Plastic and Reconstructive Surgery. Global Open·Ryan E ReboweMaurice Y Nahabedian
Mar 19, 2019·Plastic and Reconstructive Surgery. Global Open·Libby R Copeland-HalperinMark L Venturi
May 3, 2019·Plastic and Reconstructive Surgery. Global Open·Oscar J ManriqueSteven R Jacobson
Jun 18, 2019·Plastic and Reconstructive Surgery·John Ys KimMegan Fracol
Jul 2, 2019·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Lun LiJiong Wu
Jul 28, 2019·Plastic and Reconstructive Surgery·John Y S KimMegan Fracol
Sep 7, 2019·The Breast : Official Journal of the European Society of Mastology·Roland ReitsamerAndreas Sir
Oct 18, 2019·Yeungnam University Journal of Medicine·Sung-Eun Kim
Oct 31, 2019·Annals of Plastic Surgery·Shayda J MirhaidariDouglas S Wagner
Dec 21, 2019·Plastic and Reconstructive Surgery·Joseph BanuelosNho V Tran
Dec 21, 2019·Plastic and Reconstructive Surgery·Michael C HollandHani Sbitany

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Cancer: Chemo-Resistance

Some cancers are difficult to treat and aggressive including the "triple-negative" breast cancer. This type of cancer is chemoresistant even before chemotherapy begins. Here are the latest discoveries chemo-resistance in breast cancer.