Meta-analysis of randomized studies evaluating chewing gum to enhance postoperative recovery following colectomy

Archives of Surgery
Sanjay PurkayasthaParis P Tekkis

Abstract

To compare outcomes following abdominal surgery with or without the use of chewing gum in the early postoperative period. MEDLINE, Embase, Ovid, and Cochrane databases. Randomized controlled trials reporting 1 or more outcomes related to functional postoperative recovery. Study quality was assessed using a validated scale. Time to the first passage of flatus, time to first bowel movement, and length of postoperative stay. Five trials (158 patients) satisfied the inclusion criteria. Time (in days) for the patient to pass flatus (weighted mean difference [WMD], - 0.66; 95% confidence interval [CI], - 1.11 to - 0.20; P = .005) and the time until the first bowel movement (WMD, - 1.10; 95% CI, - 1.79 to - 0.42; P = .002) were significantly reduced in the chewing gum group compared with controls. However, both of these results demonstrated significant heterogeneity. Postoperative length of stay was also reduced in the chewing gum group by longer than 1 day (WMD, - 1.25; 95% CI, - 3.27 to 0.77; P = .23); however, this result was not statistically significant. This result was significant when studies that explicitly included patients with stomas being formed during the surgery were excluded (WMD, - 2.46; 95% CI, - 3.14 to - 1.79; P < ....Continue Reading

Associated Clinical Trials

Apr 24, 2012·Gabriela López Jaimez, Gabriela López Jaimez

Citations

May 24, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·P AlfonsiUNKNOWN le groupe de travail de la Société française d’anesthésie et réanimation (Sfar) et de la Société française de chirurgie dige
Feb 24, 2010·International Journal of Colorectal Disease·Hasan Al ChalabiPaul Neary
Feb 2, 2010·Clinics in Colon and Rectal Surgery·James Carroll, Karim Alavi
Oct 2, 2013·Iranian Red Crescent Medical Journal·Farideh Mohsenzadeh LedariSoriya Khafri
Nov 29, 2012·Annals of Surgical Oncology·Gary DengBarrie Cassileth
Nov 28, 2012·Journal of Anesthesia·Guilherme Holck, William Camann
May 10, 2016·Complementary Therapies in Clinical Practice·Sacide Yildizeli Topcu, Seher Deniz Oztekin
Oct 18, 2014·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·A Tazegül PekinÇ Çelik
Apr 26, 2011·Emergency Medicine Clinics of North America·Geoffrey E Hayden, Kevin L Sprouse
Mar 17, 2010·European Urology·Nathan LawrentschukManfred P Wirth
Apr 1, 2009·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·Heather J Ipema, Julie Golembiewski
Jun 16, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·K H I Abd-El-MaeboudM F Fikry
Dec 17, 2011·Paediatric Anaesthesia·Thomas J Poulton
Jun 8, 2012·Journal of Clinical Nursing·Shin Yi JangKyeong Sug Kim
Jun 21, 2016·International Journal of Surgery·Gabriela López-Jaimez, Carlos A Cuello-García
Dec 26, 2015·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Elles Steenhagen
Oct 21, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C M ByrneC J Young
Apr 29, 2015·The Cochrane Database of Systematic Reviews·Vaneesha ShortStephen J Lewis
Jan 5, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nefise Nazlı YenigulIsıl Ayhan
Dec 4, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Wenceslao VásquezJose Luis Garcia-Sabrido
Mar 19, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·Y-P ZhuD-W Ye
Mar 17, 2010·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Barbara J HocevarMikel Gray
May 9, 2014·Diseases of the Colon and Rectum·Cheng-Le ZhuangZhen Yu

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