Meta-analysis of risk of developing malignancy in congenital choledochal malformation

The British Journal of Surgery
A Ten HoveR H J de Kleine

Abstract

Choledochal malformations comprise various congenital cystic dilatations of the extrahepatic and/or intrahepatic biliary tree. Choledochal malformation is generally considered a premalignant condition, but reliable data on the risk of malignancy and optimal surgical treatment are lacking. The objective of this systematic review was to assess the prevalence of malignancy in patients with choledochal malformation and to differentiate between subtypes. In addition, the risk of malignancy following cystic drainage versus complete cyst excision was assessed. A systematic review of PubMed and Embase databases was performed in accordance with the PRISMA statement. A meta-analysis of the risk of malignancy following cystic drainage versus complete cyst excision was undertaken in line with MOOSE guidelines. Prevalence of malignancy was defined as the rate of biliary cancer before resection, and malignant transformation as new-onset biliary cancer after surgery. Eighteen observational studies were included, reporting a total of 2904 patients with a median age of 36 years. Of these, 312 in total developed a malignancy (10·7 per cent); the prevalence of malignancy was 7·3 per cent and the rate of malignant transformation was 3·4 per cent. ...Continue Reading

References

Dec 1, 1994·Journal of Pediatric Surgery·T M TsangP Chamberlain
Dec 13, 1997·Journal of Pediatric Surgery·H SaingP K Tam
Feb 4, 1998·The British Journal of Surgery·T IshibashiK Kanazawa
Feb 14, 1998·BMJ : British Medical Journal·M EggerG Davey Smith
Sep 30, 1998·Annales de chirurgie·J LerutJ F Gigot
May 24, 2001·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·M ImazuS Ono
Apr 3, 2002·Archives of Surgery·Chi-Leung LiuJohn Wong
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Mar 17, 2004·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Michael NichollLayton F Rikkers
Jun 12, 2004·American Journal of Surgery·Paul H JordanKaren L Woods
Jun 19, 2004·BMJ : British Medical Journal·David AtkinsUNKNOWN GRADE Working Group
Aug 11, 2004·Archives of Surgery·Brendan C VisserSang-Mo Kang
Nov 20, 2004·ANZ Journal of Surgery·Shih-Ping ChengTsang-Pai Liu
May 3, 2005·American Journal of Surgery·Kevin WisemanCharles H Scudamore
Dec 26, 2006·Annals of Surgical Oncology·Kjetil Søreide, Jon Arne Søreide
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Oct 21, 2009·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·Rajeev DhuparT Clark Gamblin
Feb 16, 2010·Journal of Pediatric Surgery·Shigeru OnoNaomi Iwai
Apr 28, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Ching Shui HuangDer Fang Chen
Oct 1, 2010·Annals of Surgery·Kathryn M ZieglerJay L Grosfeld
Mar 2, 2011·World Journal of Surgery·Min-Jeong ChoSung-Gyu Lee
Mar 30, 2011·Archives of Disease in Childhood·Erica Makin, Mark Davenport
Jul 5, 2011·The British Journal of Surgery·C TurowskiM Davenport
Oct 19, 2011·Archives of Surgery·Seung Eun LeeUNKNOWN Korean Pancreas Surgery Club
Sep 20, 2012·Journal of Gastroenterology and Hepatology·Taku OhashiYoichi Ajioka
Aug 5, 2015·Gastroenterology Research and Practice·Hong-Tian XiaJia-Hong Dong
Aug 11, 2015·Gastroenterology Research and Practice·Norman Oneil MachadoShahzad Younas
Jun 5, 2016·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Maitham A MoslimGareth Morris-Stiff

❮ Previous
Next ❯

Citations

Jan 14, 2020·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Didi ZhuansunJiexiong Feng
Jun 21, 2020·Liver International : Official Journal of the International Association for the Study of the Liver·Ruben H de KleineRobert J Porte
Jun 30, 2019·BMJ Case Reports·Belén Aneiros CastroMónica De Miguel Moya
Sep 11, 2019·BJR Case Reports·Nicola TaralloCarlo Fugazzola
Nov 7, 2019·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M Dübbers
Jan 3, 2021·Abdominal Radiology·Dhakshinamoorthy GaneshanCatherine Devine
Dec 15, 2020·Curēus·Narendra PanditShailesh Adhikary
Dec 19, 2020·Endoscopy·Vincenzo Giorgio MiranteRomano Sassatelli
May 2, 2021·International Journal of Surgery Case Reports·Sujan ShresthaSumita Pradhan
May 11, 2021·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Cecilia FerrariSantiago Sánchez-Cabús
Jun 18, 2021·International Journal of Surgery Case Reports·Sushil GyawaliRamesh Singh Bhandari
Aug 27, 2021·World Journal of Clinical Cases·Xin WuXiao-Dong He
May 31, 2019·Case Reports in Gastroenterology·Anneke Ten HoveJoost M Klaase
May 2, 2020·Case Reports in Gastroenterology·Sindhura KolliKrishna Gurram

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection
prophylactic surgery

Software Mentioned

SPSS
Embase
MOOSE
RevMan Manager

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición
L Vázquez-ValdésS Cárdenas
JSLS : Journal of the Society of Laparoendoscopic Surgeons
Edward S ChanEric S Hungness
© 2022 Meta ULC. All rights reserved