Meta-Analysis of Risks for Short-Term Readmission in Patients With Heart Failure

The American Journal of Cardiology
Makoto SaitoThomas H Marwick

Abstract

This investigation sought to quantify the risk factors for short-term readmission in patients with heart failure (HF). Electronic databases were systematically searched for studies reporting relative risk, odds ratio, and hazard ratio for the combined primary outcome of all-cause hospital readmission or all-cause mortality ≤90 days from discharge of patients with HF. Clinical characteristics, study design, type and incidence of outcome, univariable effect sizes for each risk factor, and their associated 95% confidence intervals were extracted. Each univariable effect size was pooled and computed in a separate meta-analysis using random-effects models weighted by inverse variance. The frequency of significance of each risk factor in multivariable models was also assessed to confirm their independence. Sixty-nine studies (2,038,524 patients) were included and 144 factors were reported, including 32 reported more than twice. The significant associations of the combined primary outcome were chronic lung disease, chronic kidney disease, atherosclerotic vascular disease (peripheral, coronary, and cerebrovascular), diabetes, anemia, lower systolic blood pressure, previous admission, multidisciplinary treatment, and use of beta-blockad...Continue Reading

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Citations

Jun 20, 2017·JBI Database of Systematic Reviews and Implementation Reports·Inge SchjødtBrian Bridal Løgstrup
Apr 11, 2018·Research in Gerontological Nursing·Yousef AyatollahiJi Won Yoo
Mar 6, 2019·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Yun YeLorena Baccaglini
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Nov 30, 2018·Heart Failure Reviews·David GoldgrabSara R Tabtabai
Dec 18, 2019·International Journal of Environmental Research and Public Health·Masahiro KitamuraPeter H Brubaker
Feb 6, 2021·Heart, Lung & Circulation·Eun Sun ChoiVasiliki Betihavas
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Feb 8, 2018·Journal of Cardiac Failure·D Marshall BrinkleyLynne W Stevenson

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