Jan 12, 2017

Meta-Analysis of the Long Term Success Rate of Different Interventions in Benign Biliary Strictures

PloS One
Orsolya HuszárÁkos Szücs

Abstract

Benign biliary stricture is a rare condition and the majority of the cases are caused by operative trauma or chronic inflammation based on various etiology. Although the initial results of endoscopic, percutaneous and surgical treatment are impressive, no comparison about long term stricture resolution is available. The goal of this study was to compare the long term disease free survival in benign biliary strictures with various etiology after surgery, percutaneous transhepatic-and endoscopic treatment. PubMed, Embase, and Cochrane Library were searched by computer and manually for published studies. The investigators selected the publications according to the inclusion and exclusion criteria, processed the data and assessed the quality of the selected studies. Meta-analysis of data of 24 publications was performed to compare long term disease free survival of different treatment groups. Compared the subgroups surgery resulted in the highest long term stricture resolution rate, followed by the percutaneous transhepatic treatment, the multiple plastic stent insertion and covered self-expanding metal stents (SEMS), however the difference was not significant. All compared methods are significantly superior to the single plastic s...Continue Reading

Mentioned in this Paper

Endoscopy (Procedure)
Study
Jaundice, Obstructive
Diagnostic Radiology Modality
Anatomical Anastomosis
Biliary Tract Diseases
Meta-Analysis (Publications)
Meta Analysis (Statistical Procedure)
Surgical Endoscopy
Percutaneous

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